Actarit
- CAS NO.:18699-02-0
- Empirical Formula: C10H11NO3
- Molecular Weight: 193.2
- MDL number: MFCD00196165
- EINECS: 242-511-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 21:13:59
What is Actarit?
Description
Actarit is an orally administered disease-modifying antirheumatic drug launched in Japan. Although its structure resembles that of non-steroidal anti-inflammatory drugs, it has no effect on experimental acute inflammation and has no analgesic or antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are mediated via modulation of production and serum level of interleukin-2 which enhances production of suppressor T-cells to the immune system, thereby, preventing development of articular lesions.
Chemical properties
Crystalline Solid
Originator
Nippon Shlnyaku;Mltaublshl Kasel (Japan)
The Uses of Actarit
Antiarthritic
The Uses of Actarit
Chronic rheumatoid arthritis
What are the applications of Application
Actarit is Actarit is an anti-arthritic.
Definition
ChEBI: Actarit is an anilide and a member of acetamides.
brand name
Orcl; Mover
Purification Methods
Crystallise the acid from MeOH/Me2CO, aqueous EtOH or H2O. The amide has m 231o (from 50% aqueous EtOH). [Gabriel Chem Ber 15 841 1882, Cerecedo et al. J Biol Chem 42 238 1924, Tramontano et al. J Am Chem Soc 110 2282 1988, Beilstein 14 II 281.]
Properties of Actarit
Melting point: | 173-175°C |
Boiling point: | 449.1±28.0 °C(Predicted) |
Density | 1.288±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO, Ethanol, Methanol |
form | Solid |
pka | 4.34±0.10(Predicted) |
color | White to Off-White |
Merck | 14,133 |
CAS DataBase Reference | 18699-02-0(CAS DataBase Reference) |
Safety information for Actarit
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Actarit
Abamectin manufacturer
Varanous Labs Pvt Ltd
BASR Fine Chemicals Pvt. Ltd.
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