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HomeProduct name listAC-DEVD-PNA

AC-DEVD-PNA

Synonym(s):Ac-DEVD-pNA

AC-DEVD-PNA Structural

What is AC-DEVD-PNA?

The Uses of AC-DEVD-PNA

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase.

The Uses of AC-DEVD-PNA

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32.

The Uses of AC-DEVD-PNA

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

What are the applications of Application

Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

Properties of AC-DEVD-PNA

Boiling point: 1191.1±65.0 °C(Predicted)
Density  1.448±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO (Slightly), Methanol (Slightly, Heated)
pka 2.97±0.10(Predicted)
form  powder
color  white
Water Solubility  Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).
Stability: Hygroscopic

Safety information for AC-DEVD-PNA

Computed Descriptors for AC-DEVD-PNA

Related products of tetrahydrofuran

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