9-methoxycamptothecin
- CAS NO.：19685-10-0
- Empirical Formula: C21H18N2O5
- Molecular Weight: 378.38
- EINECS: 2017-001-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is 9-methoxycamptothecin?
Description
A minor constituent of Mappia foetida Miers. The alkaloid yields pale yellow crystals when purified from CHC13-MeOH. It is laevorotatory with [α]24D - 77.5° (c 1.0, pyridine). The structure has been established by spectroscopic methods.
The Uses of 9-methoxycamptothecin
9-Methoxycamptothecin is an alkaloid derivative of Camptothecin (C175150) derivative used in the treatment of cancers. Camptothecin is a potent anti-cancer agent.
The Uses of 9-methoxycamptothecin
10-Methoxycamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases.
References
Govindachari, Viswanathan., Phytochem., 11, 3529 (1972)
Govindachari, Viswanathan.,Ind. J. Chem., 10,453 (1972)
Properties of 9-methoxycamptothecin
| Melting point: | 254-255℃ |
| Boiling point: | 773.1±60.0 °C(Predicted) |
| Density | 1.50 |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Cryst. |
| pka | 11.21±0.20(Predicted) |
| color | White to yellow |
Safety information for 9-methoxycamptothecin
Computed Descriptors for 9-methoxycamptothecin
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