8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
Synonym(s):8-Br-A-3:5-MP;8-Br-cAMP;8-Bromo-cAMP
- CAS NO.：23583-48-4
- Empirical Formula: C10H11BrN5O6P
- Molecular Weight: 408.1
- MDL number: MFCD00075580
- EINECS: 245-760-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE?
Chemical properties
White powder
The Uses of 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
8-Bromoadenosine 3′,5′-cyclic monophosphate has been used:
- to treat H295R cells as positive controls for CYP19 induction
- as a membrane permeable cAMP analog to study its effect on short-circuit current (Isc)
- to investigate its potential as an inducer of differentiation in Wharton′s jelly-derived mesenchymal stem cells (WJ-MSCs)
What are the applications of Application
8-Bromoadenosine 3′,5′-cyclic monophosphate is a membrane-permeable cAMP analog
Definition
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase.
Biochem/physiol Actions
8-bromo-adenosine?3′,5′-cyclic?monophosphate?(8-bromo-cAMP), added to hepatocytes during plating helps to increase the acquisition of beta-adrenoceptors.
Properties of 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
| Melting point: | 254 °C (dec.) (lit.) |
| Boiling point: | 741.9±70.0 °C(Predicted) |
| Density | 2.80±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | aqueous base: soluble |
| form | Powder |
| pka | 0.95±0.60(Predicted) |
| color | Pale Brown |
| Sensitive | Hygroscopic |
| BRN | 591930 |
Safety information for 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
Computed Descriptors for 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
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