8-BROMOADENOSINE
Synonym(s):6-Amino-8-bromopurine riboside;8-Bromoadenine-9-β-D -ribofuranoside
- CAS NO.：2946-39-6
- Empirical Formula: C10H12BrN5O4
- Molecular Weight: 346.14
- MDL number: MFCD00005733
- EINECS: 220-959-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 8-BROMOADENOSINE?
Description
8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.
Chemical properties
Off-White Solid
The Uses of 8-BROMOADENOSINE
8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.
What are the applications of Application
8-Bromoadenosine is an adenosine binding inhibitor
Definition
ChEBI: 8-Bromoadenosine is a purine nucleoside.
Properties of 8-BROMOADENOSINE
| Melting point: | 210-212 °C (dec.)(lit.) |
| Boiling point: | 717.7±70.0 °C(Predicted) |
| Density | 1.8171 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| form | powder |
| pka | 12.89±0.70(Predicted) |
| color | white |
| Water Solubility | Soluble in DMSO, and DMF. Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 627737 |
| CAS DataBase Reference | 2946-39-6(CAS DataBase Reference) |
Safety information for 8-BROMOADENOSINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 8-BROMOADENOSINE
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product: 2946-39-6 8-Bromoadenosine 99%
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![8-BROMO-ADENOSINE-5'-[(BETA,GAMMA)-IMIDO]TRIPHOSPHATE, SODIUM SALT](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB7122831.gif)
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