8-BROMO-CADP-RIBOSE
Synonym(s):Br-cADPR;Br-cADP-ribose
- CAS NO.：151898-26-9
- Empirical Formula: C15H20BrN5O13P2
- Molecular Weight: 620.2
- MDL number: MFCD00274402
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 8-BROMO-CADP-RIBOSE?
Chemical properties
white lyophilized powder
What are the applications of Application
8-Bromo-cADP-Ribose (8-Br-cADPR) is a cell permeable antagonist of cADPR, shown to block cADPR from inducing Ca2+ release.
Biochem/physiol Actions
An antagonist of cyclic ADP-ribose (cADPR), and an endogenous metabolite of β-NAD+. cADPR has been shown to regulate calcium release from the endoplasmic and sarcoplasmic reticulum. In cells, cADPR is synthesized by ADP-ribosyl cyclase or CD38, a lymphocyte differentiation antigen.
Properties of 8-BROMO-CADP-RIBOSE
| Boiling point: | 941.8±75.0 °C(Predicted) |
| Density | 2.78±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: 5 mg/mL |
| form | lyophilized powder |
| pka | 0.97±0.70(Predicted) |
| color | white |
Safety information for 8-BROMO-CADP-RIBOSE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 8-BROMO-CADP-RIBOSE
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