8-AZAGUANINE
- CAS NO.：134-58-7
- Empirical Formula: C4H4N6O
- Molecular Weight: 152.11
- MDL number: MFCD00056937
- EINECS: 205-148-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 08:26:49
What is 8-AZAGUANINE?
Chemical properties
yellow powder
The Uses of 8-AZAGUANINE
8-Azaguanine, is a purine analogue which shows antineoplastic activity.
The Uses of 8-AZAGUANINE
Antineoplastic;Purine antimetabolite
What are the applications of Application
8-Azaguanine is a triazolo guanine analog that inhibits purine nucleotide biosynthesis and shows antineoplastic activity.
Definition
ChEBI: A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
Hazard
Mitotoic poison.
Purification Methods
Dissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.]
Properties of 8-AZAGUANINE
| Melting point: | >300 °C(lit.) |
| Boiling point: | 274.55°C (rough estimate) |
| Density | 1.5579 (rough estimate) |
| refractive index | 2.3000 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly) |
| pka | 6.75±0.20(Predicted) |
| form | lyophilized powder |
| color | White to yellow |
| Merck | 896 |
| CAS DataBase Reference | 134-58-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 8-Azaguanine(134-58-7) |
| EPA Substance Registry System | 8-Azaguanine (134-58-7) |
Safety information for 8-AZAGUANINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P501:Dispose of contents/container to..… |
Computed Descriptors for 8-AZAGUANINE
| InChIKey | LPXQRXLUHJKZIE-UHFFFAOYSA-N |
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