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HomeProduct name list7-METHOXY-3-INDAZOLECARBOXYLIC ACID

7-METHOXY-3-INDAZOLECARBOXYLIC ACID

7-METHOXY-3-INDAZOLECARBOXYLIC ACID Structural

What is 7-METHOXY-3-INDAZOLECARBOXYLIC ACID?

The Uses of 7-METHOXY-3-INDAZOLECARBOXYLIC ACID

7-Methoxy-1H-indazole-3-carboxylic Acid is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.

Properties of 7-METHOXY-3-INDAZOLECARBOXYLIC ACID

storage temp.  2-8°C

Safety information for 7-METHOXY-3-INDAZOLECARBOXYLIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 7-METHOXY-3-INDAZOLECARBOXYLIC ACID

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