7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
Synonym(s):N-Succinimidyl 7-(diethylamino)coumarin-3-carboxylate
- CAS NO.:139346-57-9
- Empirical Formula: C18H18N2O6
- Molecular Weight: 358.35
- MDL number: MFCD00467585
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER?
The Uses of 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
Derivatives of 7-aminocoumarins are the most extensively utilized labeling reagents for preparing brightly blue fluorescent conjugates of proteins and nucleic acid. The flourescent-labelling better matches the excitation-wavelength of standard blue lasers
The Uses of 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester is an amine reactive fluorescent probe.
Properties of 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
Boiling point: | 559.3±60.0 °C(Predicted) |
Density | 1.40±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | DMF: soluble |
pka | 2.60 ± 0.20, most basic, temperature:
25 °C |
form | Solid |
color | Yellow solid;Bright yellow solid;Orange powder |
λmax | 442 nm (Buffer pH 9) |
BRN | 5359433 |
Major Application | Silica particles/beads |
Biological Applications | Detecting aminoacids, hydrogen peroxide, metal ions/smallmolecules; detecting/identifying uronium salts;identifying chromosome,genome; monitoringproteolysis;quantifying analytes;as a substrate formeasuring extracellular matrix metalloprotease (MMP-1)activity, proteases activity; measuring lysosomalmembrane potential in situ; colloidal diagnosticdevices; useful for synthesizing peptides |
Safety information for 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
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7-(Diethylamino)coumarin-3-carboxylic acid
4-(N,N-DIETHYLAMINO)CINNAMIC ACID
7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID, SUCCINIMIDYL ESTER
(2,5-Dioxopyrrolidin-1-yl) 2-oxochromene-3-carboxylate
4-(Dimethylamino)cinnamic acid
N-ACRYLOXYSUCCINIMIDE
DEAC, SE [7-Diethylaminocoumarin-3-carboxylic acid, succinimidyl ester]
Coumarin
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