7-(Diethylamino)coumarin-3-carboxylic acid
- CAS NO.：50995-74-9
- Empirical Formula: C14H15NO4
- Molecular Weight: 261.27
- MDL number: MFCD00068721
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:05
What is 7-(Diethylamino)coumarin-3-carboxylic acid?
The Uses of 7-(Diethylamino)coumarin-3-carboxylic acid
7-(Diethylamino)coumarin-3-carboxylic acid is an amine-reactive fluorescent label used for protein conjugation.
The Uses of 7-(Diethylamino)coumarin-3-carboxylic acid
7-(Diethylamino)-coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.
What are the applications of Application
7-(Diethylamino)coumarin-3-carboxylic acid is an amine-reactive fluorescent label used for protein conjugation
Properties of 7-(Diethylamino)coumarin-3-carboxylic acid
| Melting point: | 222-224 °C (dec.)(lit.) |
| Boiling point: | 464.7±45.0 °C(Predicted) |
| Density | 1.317±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMF: soluble |
| form | Solid |
| pka | -98.36 ± 0.20, most acidic, temperature:
25 °C; 6.06 ± 0.20, most basic(at 25℃) |
| color | Bright orange solid; Orange crystals;
Orange crystalline solid; Orange laths; Orange
powder; Orange solid |
| λmax | 409 nm (Buffer pH 9.0) |
| BRN | 6145963 |
| Major Application | Epoxy resinsphotoluminescent devices;lithographic platematerials; oil-repellent copolymers/coatings;polymer matrices; silica nanoparticles for imaging,security, and sensing applications |
| Biological Applications | Detecting hydrogenperoxide; evaluating iron ions; cysteine cathepsinsinhibitors; β-glucosidase inhibitors; humanmonoamine oxidase inhibitors; N-Methyl-D-aspartatereceptors (NMDARs) inhibitors; phosphateassay; probing actomyosin mechanism;treatingcancer/antitumor activity，treating cognitive deficits orschizophrenia;as a substrate for measuring proteinkinase activity |
Safety information for 7-(Diethylamino)coumarin-3-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 7-(Diethylamino)coumarin-3-carboxylic acid
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