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HomeProduct name list6,9-Dichloro-2-methoxyacridine

6,9-Dichloro-2-methoxyacridine

  • CAS NO.:86-38-4
  • Empirical Formula: C14H9Cl2NO
  • Molecular Weight: 278.13
  • MDL number: MFCD00005028
  • EINECS: 201-666-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
6,9-Dichloro-2-methoxyacridine Structural

What is 6,9-Dichloro-2-methoxyacridine?

The Uses of 6,9-Dichloro-2-methoxyacridine

6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.

General Description

6,9-Dichloro-2-methoxyacridine on reaction with quinolizidinylalkylamines yields 4-aminoquinoline and 9-aminoacridine derivatives.

Purification Methods

Crystallise it from *benzene or 1,2-dichloroethane (m 162-163o). [Hall & Turner J Chem Soc 697 1945, Beilstein 21 III/IV 1553.]

Properties of 6,9-Dichloro-2-methoxyacridine

Melting point: 163-165 °C (lit.)
Boiling point: 444.3±25.0 °C(Predicted)
Density  1.52 g/cm3
storage temp.  2-8°C
pka 2.98±0.10(Predicted)
Water Solubility  Insoluble in water.
BRN  226309
CAS DataBase Reference 86-38-4(CAS DataBase Reference)

Safety information for 6,9-Dichloro-2-methoxyacridine

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H334:Sensitisation, respiratory
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 6,9-Dichloro-2-methoxyacridine

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