6,9-Dichloro-2-methoxyacridine
- CAS NO.:86-38-4
- Empirical Formula: C14H9Cl2NO
- Molecular Weight: 278.13
- MDL number: MFCD00005028
- EINECS: 201-666-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 6,9-Dichloro-2-methoxyacridine?
The Uses of 6,9-Dichloro-2-methoxyacridine
6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.
General Description
6,9-Dichloro-2-methoxyacridine on reaction with quinolizidinylalkylamines yields 4-aminoquinoline and 9-aminoacridine derivatives.
Purification Methods
Crystallise it from *benzene or 1,2-dichloroethane (m 162-163o). [Hall & Turner J Chem Soc 697 1945, Beilstein 21 III/IV 1553.]
Properties of 6,9-Dichloro-2-methoxyacridine
Melting point: | 163-165 °C (lit.) |
Boiling point: | 444.3±25.0 °C(Predicted) |
Density | 1.52 g/cm3 |
storage temp. | 2-8°C |
pka | 2.98±0.10(Predicted) |
Water Solubility | Insoluble in water. |
BRN | 226309 |
CAS DataBase Reference | 86-38-4(CAS DataBase Reference) |
Safety information for 6,9-Dichloro-2-methoxyacridine
Signal word | Danger |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6,9-Dichloro-2-methoxyacridine
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4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
Quinacridone
Basic Orange 14
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
2-ETHOXY-6,9-DIAMINOACRIDINE
6,9-Dichloro-2-methoxyacridine
9-Chloroacridine
4-Chloroquinoline
4-Chloro-6-hydroxyquinoline
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