6-Chlorouracil
Synonym(s):4-Chloro-2,6-dihydroxypyrimidine;6-Chloro-2,4-dihydroxypyrimidine;6-Chlorouracil
- CAS NO.：4270-27-3
- Empirical Formula: C4H3ClN2O2
- Molecular Weight: 146.53
- MDL number: MFCD00014595
- EINECS: 224-258-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-13 17:03:25
What is 6-Chlorouracil?
Chemical properties
White to off-white powder
The Uses of 6-Chlorouracil
6-Chlorouracil acts as an inhibitor of yeast alcohol dehydrogenase (ADH-H). 6-Chlorouracil is a potential inhibitor of DNA repair glycosylases.
The Uses of 6-Chlorouracil
Chlorouracil (4-Chlorouracil; 6-Chlorouracil) is a halogenated uracil that is useful in studies of the effects of halogenation on nucleic acid base-pair stability and alkali metal ion affinity. Reaction of 6-chlorouracil with 4-(dimethylamino)pyridine, 4-methylpyridine, and pyridin-4-yl-morpholine yielded pyridinium-substituted uracils as chlorides which were converted into pyridinium uracilates by deprotonation. These heterocyclic mesomeric betaines are cross-conjugated and thus possess separate cationic (pyridinium) and anionic (uracilate) moieties. Calculations and X-ray single crystal analyses may be used to characterize these systems and to compare the salts with the betaines.
Properties of 6-Chlorouracil
| Melting point: | 290-295°C |
| Boiling point: | 300°C |
| Density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in Ammonium Hydroxide |
| form | Solid |
| pka | 6.24±0.10(Predicted) |
| color | White |
| Water Solubility | 4.885g/L(25 ºC) |
| BRN | 120492 |
| InChI | InChI=1S/C4H3ClN2O2/c5-2-1-3(8)7-4(9)6-2/h1H,(H2,6,7,8,9) |
| CAS DataBase Reference | 4270-27-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 6-Chlorouracil(4270-27-3) |
Safety information for 6-Chlorouracil
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-Chlorouracil
| InChIKey | PKUFNWPSFCOSLU-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(Cl)=CC(=O)N1 |
6-Chlorouracil manufacturer
Mekong pharmaceuticals pvt ltd
1Y
Phone:+918008212221
Whatsapp: +91- 8008212221
product: 6-Chlorouracil 98%
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![6-CHLORO-1-[(3-BROMO-4-METHOXYPHENYL)METHYL]-3-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE](https://img.chemicalbook.in/CAS/GIF/121593-88-2.gif)
You may like
-
4270-27-3 98%View Details
4270-27-3 -
4270-27-3 6-Chlorouracil 98%View Details
4270-27-3 -
6-Chlorouracil CAS 4270-27-3View Details
4270-27-3 -
6-Chlorouracil, 98% CAS 4270-27-3View Details
4270-27-3 -
6-Chlorouracil CAS 4270-27-3View Details
4270-27-3 -
4270-27-3 98%View Details
4270-27-3 -
6-CHLOROURACIL CAS 4270-27-3View Details
4270-27-3 -
4-Chlorouracil CAS 4270-27-3View Details
4270-27-3
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.