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HomeProduct name list6 beta-hydroxycortisol

6 beta-hydroxycortisol

  • CAS NO.:53-35-0
  • Empirical Formula: C21H30O6
  • Molecular Weight: 378.46
  • MDL number: MFCD00200405
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:56
6 beta-hydroxycortisol Structural

What is 6 beta-hydroxycortisol?

Chemical properties

Off-White to Pale Yellow Solid

The Uses of 6 beta-hydroxycortisol

A metabolite of Cortisol

Definition

ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol.

Properties of 6 beta-hydroxycortisol

Melting point: 182-190?C
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Pale Yellow

Safety information for 6 beta-hydroxycortisol

Computed Descriptors for 6 beta-hydroxycortisol

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