Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list6-Aminonicotinic acid

6-Aminonicotinic acid

Synonym(s):6-Aminonicotinic acid

  • CAS NO.:3167-49-5
  • Empirical Formula: C6H6N2O2
  • Molecular Weight: 138.12
  • MDL number: MFCD00006326
  • EINECS: 221-630-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 08:26:49
6-Aminonicotinic acid Structural

What is 6-Aminonicotinic acid?

Chemical properties

Light yellow Cryst

The Uses of 6-Aminonicotinic acid

6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.

The Uses of 6-Aminonicotinic acid

Antiproliferative

Definition

ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.

What are the applications of Application

6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).

General Description

Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.

Purification Methods

Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]

Properties of 6-Aminonicotinic acid

Melting point: >300 °C (lit.)
Boiling point: 253.51°C (rough estimate)
Density  1.3471 (rough estimate)
refractive index  1.5100 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
form  Powder
pka 2.86±0.10(Predicted)
color  White to beige
Water Solubility  ca 1.0 g/L (20 ºC)
Merck  14,456
BRN  115992
CAS DataBase Reference 3167-49-5(CAS DataBase Reference)
NIST Chemistry Reference Nicotinic acid, 6-amino-(3167-49-5)
EPA Substance Registry System 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)

Safety information for 6-Aminonicotinic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 6-Aminonicotinic acid

Abamectin manufacturer

JSK Chemicals

1Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 3167-49-5 99%
Inquiry

Dr R R Organics

1Y
Phone:+91-9666306440
Whatsapp: +91-9666306440
product: 6-Aminonicotinic acid 98%
Inquiry

Prodev Pharma Pvt Ltd

1Y
Phone:+91-9043422844
Whatsapp: +91-9043422844
product: 6-Aminonicotinic acid 3167-49-5 98%
Inquiry

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.