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HomeProduct name list6-Aminoindole

6-Aminoindole

Synonym(s):Indol-6-ylamine;NSC 82379

  • CAS NO.:5318-27-4
  • Empirical Formula: C8H8N2
  • Molecular Weight: 132.16
  • MDL number: MFCD02093959
  • EINECS: 627-713-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
6-Aminoindole Structural

What is 6-Aminoindole?

Chemical properties

Solid

The Uses of 6-Aminoindole

Reactant for preparation of:

  • Inhibitors of mammalian target of rapamycin (mTOR ) protein
  • Inhibitors of the AcrAB-TolC efflux pump
  • Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
  • Potent DNA-topoisomerase II poisons and anti-MDR agents
  • Protein kinase C θ (PKCθ) inhibitors
  • Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
  • Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
  • 5,6-fused heteroaromatic ureas as TRPV1 antagonists
  • Allosteric enhancers of the A3 adenosine receptor
  • Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

Properties of 6-Aminoindole

Melting point: 75-79 °C
Boiling point: 161-166°C 2mm
Density  1.268±0.06 g/cm3(Predicted)
Flash point: 161-166°C/2mm
storage temp.  -20°C
solubility  soluble in Methanol
form  Crystalline Powder
pka 18.23±0.30(Predicted)
color  White to brown
Sensitive  Air Sensitive
BRN  112190
CAS DataBase Reference 5318-27-4(CAS DataBase Reference)

Safety information for 6-Aminoindole

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 6-Aminoindole

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