5-Aminoindole
Synonym(s):5-Indolamine;NSC 61452
- CAS NO.：5192-03-0
- Empirical Formula: C8H8N2
- Molecular Weight: 132.16
- MDL number: MFCD00005679
- EINECS: 225-977-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:07:02
What is 5-Aminoindole?
Chemical properties
Grey Crystals
The Uses of 5-Aminoindole
5-Aminoindole functions as a ligand for hydrophobic charge induction chromatography. A reagent for synthetic elaboration.
The Uses of 5-Aminoindole
Reactant for preparation of:
- Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
- Cytotoxic and antimitotic agents
- Insulin-like growth factor 1 receptor inhibitors
- Antitumoral agents
- Factor Xa inhibitor
- Potential antivascular agents
- Gli1-mediated transcription in the Hedgehog pathway
- Inhibitors of receptor tyrosine kinase with antiangiogenic effects
- PKCθ inhibitors
- HIV protease inhibitors
What are the applications of Application
Indolin-5-amine is a specialty product for proteomics research applications
Definition
ChEBI: An indolamine carrying an amino group at position 5.
Properties of 5-Aminoindole
| Melting point: | 131-133 °C (dec.) (lit.) |
| Boiling point: | 190 °C / 6mmHg |
| Density | 1.1083 (rough estimate) |
| refractive index | 1.6013 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| pka | 17.39±0.30(Predicted) |
| form | Crystalline Powder |
| color | Off-white to gray-brown |
| Water Solubility | insoluble |
| Sensitive | Air & Light Sensitive |
| BRN | 112348 |
| CAS DataBase Reference | 5192-03-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Aminoindole(5192-03-0) |
| EPA Substance Registry System | 5-Aminoindole (5192-03-0) |
Safety information for 5-Aminoindole
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H311:Acute toxicity,dermal H319:Serious eye damage/eye irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Aminoindole
| InChIKey | ZCBIFHNDZBSCEP-UHFFFAOYSA-N |
5-Aminoindole manufacturer
BASR Fine Chemicals Pvt. Ltd.
1Y
Phone:+91-9848230391
Whatsapp: +91-9848230391
product: 5192-03-0 98%
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