Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list4-Aminoindole

4-Aminoindole

Synonym(s):(Indol-4-yl)amine;4-Indolamine

  • CAS NO.:5192-23-4
  • Empirical Formula: C8H8N2
  • Molecular Weight: 132.16
  • MDL number: MFCD01076559
  • EINECS: 621-202-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-19 15:05:23
4-Aminoindole Structural

What is 4-Aminoindole?

Chemical properties

Greenish-grey to tan powder

The Uses of 4-Aminoindole

4-Aminoindole may be used to synthesize:

  • macrolactam tumour promoter indolactam V
  • tricyclic structure of 2-substituted-pyrrolo[2,3-h]quinolin-4-one
  • 4-azidoindole

The Uses of 4-Aminoindole

Reactant for preparation of:• ;Inhibitors of bacterial thymidylate synthase1• ;Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3• ;Protein kinase C θ (PKCθ) inhibitors4• ;Indolic non-peptidic HIV protease inhibitors5• ;Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6• ;Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7• ;11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibi

Definition

ChEBI: 4-Aminoindole is a member of indoles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 5130, 1983 DOI: 10.1021/jo00173a071

General Description

4-Aminoindole is an indole derivative. Its cytokinin activity has been assessed by tobacco pith callus bioassay. 4-Aminoindole can be prepared by reacting 2,6-dinitrotoluene and N,N-dimethylformamide dimethylacetal in anhydrous DMF.

Properties of 4-Aminoindole

Melting point: 106-109 °C (lit.)
Boiling point: 354.0±15.0 °C(Predicted)
Density  1.268±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  powder to crystal
pka 18.23±0.30(Predicted)
color  White to Gray to Brown
Water Solubility  Insoluble
Sensitive  Air Sensitive
BRN  114919
CAS DataBase Reference 5192-23-4(CAS DataBase Reference)

Safety information for 4-Aminoindole

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-Aminoindole

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.