5,6,7,8-TETRAHYDRO-1-NAPHTHOL
- CAS NO.:529-35-1
- Empirical Formula: C10H12O
- Molecular Weight: 148.2
- MDL number: MFCD00001734
- EINECS: 208-461-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-20 19:26:33
What is 5,6,7,8-TETRAHYDRO-1-NAPHTHOL?
Chemical properties
white to slightly pink crystalline mass or
The Uses of 5,6,7,8-TETRAHYDRO-1-NAPHTHOL
5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
Definition
ChEBI: 5,6,7,8-tetrahydro-1-naphthol is 1-naphthol hydrogenated at C-5, -6, -7 and -8.
Properties of 5,6,7,8-TETRAHYDRO-1-NAPHTHOL
Melting point: | 69-71 °C(lit.) |
Boiling point: | 264-265 °C705 mm Hg(lit.) |
Density | 1.0556 |
refractive index | 1.5000 (estimate) |
Flash point: | 264-265°C/705mm |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | pK1:10.28 (25°C) |
color | Off-White to Pale Orange |
BRN | 1865081 |
CAS DataBase Reference | 529-35-1(CAS DataBase Reference) |
EPA Substance Registry System | 1-Naphthalenol, 5,6,7,8-tetrahydro- (529-35-1) |
Safety information for 5,6,7,8-TETRAHYDRO-1-NAPHTHOL
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5,6,7,8-TETRAHYDRO-1-NAPHTHOL
InChIKey | SCWNNOCLLOHZIG-UHFFFAOYSA-N |
Abamectin manufacturer
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product: 529-35-1 5,6,7,8 - tetrahydronaphthalen - 1 - ol 98%
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