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HomeProduct name list5,6,7,8-TETRAHYDRO-1-NAPHTHOL

5,6,7,8-TETRAHYDRO-1-NAPHTHOL

  • CAS NO.:529-35-1
  • Empirical Formula: C10H12O
  • Molecular Weight: 148.2
  • MDL number: MFCD00001734
  • EINECS: 208-461-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-03-20 19:26:33
5,6,7,8-TETRAHYDRO-1-NAPHTHOL Structural

What is 5,6,7,8-TETRAHYDRO-1-NAPHTHOL?

Chemical properties

white to slightly pink crystalline mass or

The Uses of 5,6,7,8-TETRAHYDRO-1-NAPHTHOL

5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.

Definition

ChEBI: 5,6,7,8-tetrahydro-1-naphthol is 1-naphthol hydrogenated at C-5, -6, -7 and -8.

Properties of 5,6,7,8-TETRAHYDRO-1-NAPHTHOL

Melting point: 69-71 °C(lit.)
Boiling point: 264-265 °C705 mm Hg(lit.)
Density  1.0556
refractive index  1.5000 (estimate)
Flash point: 264-265°C/705mm
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka pK1:10.28 (25°C)
color  Off-White to Pale Orange
BRN  1865081
CAS DataBase Reference 529-35-1(CAS DataBase Reference)
EPA Substance Registry System 1-Naphthalenol, 5,6,7,8-tetrahydro- (529-35-1)

Safety information for 5,6,7,8-TETRAHYDRO-1-NAPHTHOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5,6,7,8-TETRAHYDRO-1-NAPHTHOL

InChIKey SCWNNOCLLOHZIG-UHFFFAOYSA-N

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