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HomeProduct name list5-O-Desmethyl Donepezil

5-O-Desmethyl Donepezil

5-O-Desmethyl Donepezil Structural

What is 5-O-Desmethyl Donepezil?

Chemical properties

Off-White Solid

The Uses of 5-O-Desmethyl Donepezil

A metabolite of Donepezil, an inhibitor of acetylcholinesterase

The Uses of 5-O-Desmethyl Donepezil

A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.

What are the applications of Application

5-O-Desmethyl Donepezil is an inhibitor of acetylcholinesterase (AChE)

Definition

ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.

Properties of 5-O-Desmethyl Donepezil

Melting point: 170-172°C
Boiling point: 545.3±50.0 °C(Predicted)
Density  1.190±0.06 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka 8.16±0.40(Predicted)
form  Solid
color  White to Pale Brown
CAS DataBase Reference 120013-57-2

Safety information for 5-O-Desmethyl Donepezil

Computed Descriptors for 5-O-Desmethyl Donepezil

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