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120013-57-2

120013-57-2 structural image
Product Name: 5-O-Desmethyl Donepezil
Formula: C23H27NO3
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COMPUTED DESCRIPTORS

Molecular Weight 365.5 g/mol
XLogP3 3.9
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 5
Exact Mass 365.19909372 g/mol
Monoisotopic Mass 365.19909372 g/mol
Topological Polar Surface Area 49.8 Ų
Heavy Atom Count 27
Formal Charge 0
Complexity 496
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.

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