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HomeProduct name list5-Methyltryptamine hydrochloride

5-Methyltryptamine hydrochloride

Synonym(s):3-(2-Aminoethyl)-5-methylindole hydrochloride

  • CAS NO.:1010-95-3
  • Empirical Formula: C11H15ClN2
  • Molecular Weight: 210.7
  • MDL number: MFCD00012683
  • EINECS: 213-777-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-02 15:22:07
5-Methyltryptamine hydrochloride Structural

What is 5-Methyltryptamine hydrochloride?

Chemical properties

Light Tan Solid

The Uses of 5-Methyltryptamine hydrochloride

5-Methyltryptamine hydrochloride is a methylated derivative of tryptamine, it is a weak antagonist of 5-Hydroxytryptamine (H974990) with weak potency as stimulants of the cardiac sympathetic nerves. 5-Methyltryptamine hydrochloride is also used in the preparation of inhibitors of kinesin spindle protein (KSP), a promising class of anticancer agents.

The Uses of 5-Methyltryptamine hydrochloride

  • reactant in synthesis of kinesin spindle protein (KSP) inhibitors
  • reactant in intramolecular furan Diels-Alder reactions
  • reactant in Pictet-Spengler-like reactions

Purification Methods

Recrystallise the hydrochloride from H2O. The free base has m 96-98o (from *C6H6/cyclohexane) or m 99-100o (from pet ether), and the picrate has m 243o(dec) (from EtOH). [Young J Chem Soc 3493 1958, Gaddum et al. Quart J Exp Physiol 40 49 1955, R.hm Hoppe Seyler's Z Physiol Chem 297 229 1954, Beilstein 22 III/IV 4364, 22/10 V 167.]

Properties of 5-Methyltryptamine hydrochloride

Melting point: 290-292 °C
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  Pale Beige to Light Tan
Sensitive  Hygroscopic
CAS DataBase Reference 1010-95-3

Safety information for 5-Methyltryptamine hydrochloride

Computed Descriptors for 5-Methyltryptamine hydrochloride

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