5-Methylisatin
Synonym(s):5-Methylindole-2,3-dione;NSC 9398
- CAS NO.：608-05-9
- Empirical Formula: C9H7NO2
- Molecular Weight: 161.16
- MDL number: MFCD00005721
- EINECS: 210-152-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is 5-Methylisatin?
Chemical properties
Red to brown powder or crystals
The Uses of 5-Methylisatin
Reactant for preparation of:• ;Antimycobacterial agents1• ;Promoters of central nervous system (CNS) depression in mice2• ;Inhibitors of TAK1 kinase3• ;Anti-human immunodeficiency virus (HIV) agent4• ;Potent herpes simplex virus (HSV) inhibitors5• ;Antimicrobial agents6• ;IKKβ inhibitors7• ;Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection8• ;Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors9• ;Antibacterial and anticancer agents
The Uses of 5-Methylisatin
Reactant for preparation of:
- Antimycobacterial agents
- Promoters of central nervous system (CNS) depression in mice
- Inhibitors of TAK1 kinase
- Anti-human immunodeficiency virus (HIV) agent
- Potent herpes simplex virus (HSV) inhibitors
- Antimicrobial agents
- IKKβ inhibitors
- Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection
- Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
- Antibacterial and anticancer agents
General Description
5-Methylisatin is an inhibitor of atrial natriuretic peptide (ANP) receptor coupled with guanylyl cyclase (GC).
Properties of 5-Methylisatin
| Melting point: | 180 °C (dec.) (lit.) |
| Density | 1.301±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble25mg/mL, clear to slightly hazy, orange to red |
| form | crystalline |
| pka | 10.42±0.20(Predicted) |
| color | orange |
| BRN | 123738 |
| CAS DataBase Reference | 608-05-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Methyl-2,3-indolinedione(608-05-9) |
Safety information for 5-Methylisatin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Methylisatin
5-Methylisatin manufacturer
Syn Finechem Laboratories Pvt Ltd.
1Y
Phone:+91-9848230784
Whatsapp: +91 9848230784
product: 608-05-9 5-Methylisatin 98%
BASR Fine Chemicals Pvt. Ltd.
1Y
Phone:+91-9848230391
Whatsapp: +91-9848230391
product: 5-Methylisatin 98%
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