Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list5-Hydroxyadamantan-2-one

5-Hydroxyadamantan-2-one

  • CAS NO.:20098-14-0
  • Empirical Formula: C10H14O2
  • Molecular Weight: 166.22
  • MDL number: MFCD00192211
  • EINECS: 1533716-785-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-04 20:04:50
5-Hydroxyadamantan-2-one Structural

What is 5-Hydroxyadamantan-2-one?

Description

5-Hydroxy-2-adamantanone (5-hydroxyadamantan-2-one) is a versatile starting material for synthesising various 2,5- or 1,4-disubstituted adamantanes. Chemical methods for synthesizing 5-hydroxy-2-adamantanone include disproportionation of 2-hydroxyadamantane and oxidation of 2-adamantanone. A synthetic approach to produce 5-hydroxy-2-adamantanone using P450cam (CYP101A1; a camphor monooxygenase) coupled with NADH regeneration as an oxidation biocatalyst has been reported[1].

Chemical properties

White crystal or crystalline powder

The Uses of 5-Hydroxyadamantan-2-one

anthelmintic

The Uses of 5-Hydroxyadamantan-2-one

5-Hydroxy-2-adamantanone may be used in the following studies:

  • As a model compound to investigate the application of lanthanide NMR shift reagents for the analysis of disubstituted derivative of adamantane.
  • As a starting material for the synthesis of E-2-amino-5-hydroxyadamantane.
  • As a starting material for the synthesis of 4-(triphenylsilyloxy)adamantan-1-ol.

Definition

ChEBI: Idramantone is a member of adamantanones.

brand name

INDICLOR (Nycomed Amersham).

General Description

5-Hydroxy-2-adamantanone is a disubstituted derivative of adamantane. The biocatalyzed synthesis of 5-hydroxy-2-adamantanone from 2-adamantanone has been investigated.

References

[1] Toshiki Furuya . “Biocatalytic production of 5-hydroxy-2-adamantanone by P450cam coupled with NADH regeneration.” Journal of Molecular Catalysis B-enzymatic 94 (2013): Pages 111-118.

Properties of 5-Hydroxyadamantan-2-one

Melting point: >300 °C (lit.)
Boiling point: 296.5±33.0 °C(Predicted)
Density  1.301±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO, Methanol
form  Crystalline Powder
pka 14.69±0.20(Predicted)
color  White to off-white
InChI InChI=1S/C10H14O2/c11-9-7-1-6-2-8(9)5-10(12,3-6)4-7/h6-8,12H,1-5H2
CAS DataBase Reference 20098-14-0(CAS DataBase Reference)

Safety information for 5-Hydroxyadamantan-2-one

Signal word Warning
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 5-Hydroxyadamantan-2-one

InChIKey TZBDEVBNMSLVKT-RIKBPLFRSA-N
SMILES C12CC3(O)CC(CC(C3)C1=O)C2

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.