5α-Cholestane
- CAS NO.：481-21-0
- Empirical Formula: C27H48
- Molecular Weight: 372.67
- MDL number: MFCD00066412
- EINECS: 207-562-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:52
What is 5α-Cholestane?
Description
5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads. It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.
Chemical properties
WHITE CRYSTALLINE POWDER
The Uses of 5α-Cholestane
α-Cholestane is the trans-decalin homolog of Coprostane.
The Uses of 5α-Cholestane
5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC.
What are the applications of Application
5α-Cholestane is a standard in cholesterol analysis by GC and HPLC, it is produced endogeneously in humans
Definition
ChEBI: The 5alpha-stereoisomer of cholestane.
Biochem/physiol Actions
5α-Cholestane is a sterol produced endogenously from cholesterol and has been isolated from human feces. It is derived from cholesterol by the action of intestinal microorganisms. Derivatives of 5α-cholestane in plants are called Brassinosteroids that selectively activate the PPI3K/Akt pathway.
Purification Methods
Crystallise 5-cholestane from Et2O/EtOH or EtOAc. [Ruzicka et al. Helv Chim Acta 16 327 1933, Beilstein 5 III 1132, 5 IV 1227.]
Properties of 5α-Cholestane
| Melting point: | 78-80 °C |
| Boiling point: | 250 °C (1 mmHg) |
| Density | 0.9090 |
| refractive index | 1.4887 |
| storage temp. | room temp |
| solubility | Do you have solubility information on this product that you would like to share |
| form | Crystalline Powder |
| color | White |
| Merck | 13,2219 |
| BRN | 2051806 |
| CAS DataBase Reference | 481-21-0(CAS DataBase Reference) |
| EPA Substance Registry System | Cholestane, (5.alpha.)- (481-21-0) |
Safety information for 5α-Cholestane
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 5α-Cholestane
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