5α-Cholestane

CAS NO.：481-21-0
Empirical Formula: C27H48
Molecular Weight: 372.67
MDL number: MFCD00066412
EINECS: 207-562-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is 5α-Cholestane?

Description

5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads. It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.

Chemical properties

WHITE CRYSTALLINE POWDER

The Uses of 5α-Cholestane

α-Cholestane is the trans-decalin homolog of Coprostane.

The Uses of 5α-Cholestane

5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC.

What are the applications of Application

5α-Cholestane is a standard in cholesterol analysis by GC and HPLC, it is produced endogeneously in humans

Definition

ChEBI: The 5alpha-stereoisomer of cholestane.

Biochem/physiol Actions

5α-Cholestane is a sterol produced endogenously from cholesterol and has been isolated from human feces. It is derived from cholesterol by the action of intestinal microorganisms. Derivatives of 5α-cholestane in plants are called Brassinosteroids that selectively activate the PPI3K/Akt pathway.

Purification Methods

Crystallise 5-cholestane from Et2O/EtOH or EtOAc. [Ruzicka et al. Helv Chim Acta 16 327 1933, Beilstein 5 III 1132, 5 IV 1227.]

Properties of 5α-Cholestane

Melting point:	78-80 °C
Boiling point:	250 °C (1 mmHg)
Density	0.9090
refractive index	1.4887
storage temp.	room temp
solubility	Do you have solubility information on this product that you would like to share
form	Crystalline Powder
color	White
Merck	13,2219
BRN	2051806
CAS DataBase Reference	481-21-0(CAS DataBase Reference)
EPA Substance Registry System	Cholestane, (5.alpha.)- (481-21-0)

Safety information for 5α-Cholestane

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.