Hecogenin

CAS NO.：467-55-0
Empirical Formula: C27H42O4
Molecular Weight: 430.62
MDL number: MFCD00067285
EINECS: 207-392-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is Hecogenin?

The Uses of Hecogenin

Hecogenin, is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.

The Uses of Hecogenin

antiinflammatory

Definition

ChEBI: Hecogenin is a triterpenoid.

Purification Methods

The saponin (~35 mg) in EtOAc is chromatographed on Al2O3 and eluted with *C6H6/Et2O, and the residue on evaporation is recrystallised from Me2CO. [Mazur et al. J Am Chem Soc 82 5889 1960, Marker et al. J Am Chem Soc 69 2167 1947, Beilstein 19 III/IV 2581.]

Properties of Hecogenin

Melting point:	268°C
Boiling point:	464.85°C (rough estimate)
alpha	7.2 º (c=0.8 g/100ml, CHCl3)
Density	1.0040 (rough estimate)
refractive index	1.4840 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	15.10±0.70(Predicted)
color	White to Off-White
Merck	14,4622
CAS DataBase Reference	467-55-0(CAS DataBase Reference)

Safety information for Hecogenin

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H290:Corrosive to Metals H301:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity H371:Specific target organ toxicity, single exposure H373:Specific target organ toxicity, repeated exposure H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P234:Keep only in original container. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P390:Absorb spillage to prevent material damage. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P406:Store in corrosive resistant/… container with a resistant inner liner. P403+P233:Store in a well-ventilated place. Keep container tightly closed.