(5-Carboxypentyl)(triphenyl)phosphonium bromide
- CAS NO.：50889-29-7
- Empirical Formula: C24H26BrO2P
- Molecular Weight: 457.34
- MDL number: MFCD00055556
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-09 22:15:29
What is (5-Carboxypentyl)(triphenyl)phosphonium bromide?
Chemical properties
White Crystalline Solid
The Uses of (5-Carboxypentyl)(triphenyl)phosphonium bromide
(5-Carboxypentyl)(triphenyl)phosphonium bromide is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.
Reactant for:
- Preparation of inhibitor of protein tyrosine phosphatase 1B for treatment of diabetes and obesity.
- Synthesis of folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.
- Preparation of peptide nucleic acids (PNA) with high specific activity.
- Synthesis of roseophilin via Wittig/aldol methodology.
The Uses of (5-Carboxypentyl)(triphenyl)phosphonium bromide
It is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.
Properties of (5-Carboxypentyl)(triphenyl)phosphonium bromide
| Melting point: | 197-201 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in Chloroform and Methanol. |
| form | Solid |
| color | White to Off-White |
| Sensitive | Hygroscopic |
| CAS DataBase Reference | 50889-29-7(CAS DataBase Reference) |
Safety information for (5-Carboxypentyl)(triphenyl)phosphonium bromide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for (5-Carboxypentyl)(triphenyl)phosphonium bromide
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