4-(Trimethylsilyl)-3-butyn-2-one
- CAS NO.：5930-98-3
- Empirical Formula: C7H12OSi
- Molecular Weight: 140.26
- MDL number: MFCD00190212
- EINECS: 628-294-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 4-(Trimethylsilyl)-3-butyn-2-one?
Chemical properties
clear slightly yellow liquid
The Uses of 4-(Trimethylsilyl)-3-butyn-2-one
4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475).
General Description
4-(Trimethylsilyl)-3-butyn-2-one is a ketone. Its asymmetric bioreduction to enantiopure {(S)-TMSBOL in various hydrophilic ionic liquid (ILs) solvent systems has been reported.
Properties of 4-(Trimethylsilyl)-3-butyn-2-one
| Melting point: | 99 °C |
| Boiling point: | 156 °C(lit.) |
| Density | 0.854 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 83 °F |
| storage temp. | Flammables area |
| form | clear liquid |
| Specific Gravity | 0.854 |
| color | Colorless to Light yellow to Light orange |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| CAS DataBase Reference | 5930-98-3(CAS DataBase Reference) |
Safety information for 4-(Trimethylsilyl)-3-butyn-2-one
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(Trimethylsilyl)-3-butyn-2-one
New Products
Tubulysin I Tubulysin C 2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Potassium HMDS (1.0 M in THF) 2H-Pyran, 4-ethynyltetrahydro- 2,2-Difluoropropanol 4-(Benzyloxy)-3-bromophenylacetic Acid 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 4,4-DIFLUOROCYCLOHEXANAMINE 1-(1,1-Difluoroethyl)-2-fluorobenzene (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell Imeglimin Hydrochloride IH Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
You may like
-
4-(Trimethylsilyl)-3-butyn-2-one CAS 5930-98-3View Details
5930-98-3 -
4-(Trimethylsilyl)-3-butyn-2-one CAS 5930-98-3View Details
5930-98-3 -
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.