4-Nitrophenylacetic acid
- CAS NO.：104-03-0
- Empirical Formula: C8H7NO4
- Molecular Weight: 181.15
- MDL number: MFCD00007383
- EINECS: 203-168-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 4-Nitrophenylacetic acid?
Chemical properties
Beige to yellow crystalline powder
4-Nitrophenylacetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the para- position by a nitro group.
The Uses of 4-Nitrophenylacetic acid
Intermediate for dyestuffs, pharmaceuticals, penicillin precursors, local anesthetics.
The Uses of 4-Nitrophenylacetic acid
(4-Nitrophenyl)acetic Acid used in the synthesis of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones which may act as angiogenesis inhibitors. Also used in the one step construction of amino-substituted squaraine dye.
Definition
ChEBI: A monocarboxylic acid that is phenylacetic acid carrying a nitro substituent at position 4.
Safety Profile
Moderately toxic intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Purification Methods
Crystallise the acid from EtOH/water (1:1), then from sodium-dried diethyl ether and dry it over P2O5 in vacuo. The styphnate has m 196.5-197o (prisms from EtOH). The amide has m 191o (from EtOH). [Beilstein 9 III 2284, 9 IV 1698.]
Properties of 4-Nitrophenylacetic acid
| Melting point: | 150-155 °C(lit.) |
| Boiling point: | 314.24°C (rough estimate) |
| Density | 1.4283 (rough estimate) |
| refractive index | 1.5468 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| pka | 3.85(at 25℃) |
| color | Beige to yellow |
| PH | 2.98 at 22.8℃ and 10g/L |
| Water Solubility | slightly soluble |
| Merck | 14,6621 |
| BRN | 1911801 |
| CAS DataBase Reference | 104-03-0(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Nitrophenylacetic acid (104-03-0) |
Safety information for 4-Nitrophenylacetic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Nitrophenylacetic acid
| InChIKey | YBADLXQNJCMBKR-UHFFFAOYSA-N |
4-Nitrophenylacetic acid manufacturer
Sanpra Synthesis Private Limited
2Y
Phone:+91-9246161600
Whatsapp: +91- 9246161600
product: 4-NITRO PHENYL ACETIC ACID
EPOCH LABS
2Y
Phone:+91-9515109812
Whatsapp: +91- 7702174901
product: 104-03-0 4-Nitrophenylacetic acid 99%
Synocule Research Labs Pvt Ltd
2Y
Phone:+91-9000991562
Whatsapp: +91- 9000991562
product: 4-Nitrophenylacetic acid 98%
GRK RESEARCH LABORATORIES PVT LTD
2Y
Phone:+91-7093001765
Whatsapp: +91- 7093001765
product: 4-Nitrophenylacetic acid 104-03-0 98%+
JSK Chemicals
2Y
Phone:+91-9879767970
Whatsapp: +91-9879767970
product: 104-03-0 4-Nitrophenylacetic acid, 95% 99%
SETV ASRV LLP
1Y
Phone:+91-9731133411
Whatsapp: +91- 9731133411
product: 4-Nitrophenylaceticacid 104-03-0 95-99 %
Flavi Pharma
1Y
Phone:+91-9637442284
Whatsapp: +91-9637442284
product: (2-(4-nitrophenyl) acetic acid) 104-03-0 98%
Qualychem
Andhra Pradesh
Phone:91-40-9618013520
Whatsapp: 91-40-9618013520
product: 4-Nitrophenylacetic acid
New Products
Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2,2-Difluoropropylamine hydrochloride tert-butyl 3-bromoazetidine-1-carboxylate (R)-1-Boc-3-hydroxypyrrolidine DIFLUOROACETIC ANHYDRIDE 2,2-Difluoropropionic acid Diallylamine, 99% Calcium hydroxide, 95% Aluminum oxide, basic 2-Bromophenylacetonitrile, 97% L-tert-Leucine,97% N-Hydroxy-2-methylpropanimidamide 4-(3,4-Dichlorophenyl)-3,4-Dihydro-N-Methyl-1-(2H)-Naphthalenimine (Schiff Base) 2-AMINO-3,5-DIBROMO BENZALDEHYDE [ADBA] L-Glutamic Acid Dimethyl Ester Hcl 10-Methoxy-5H-dibenz[b,f]azepine 5-Cyanophthalide N, N-Carbonyldiimidazole (CDI) Dibenzoyl Peroxide Titanium Dioxide 2-(Methylthio) Benzonitrile Sodium Acetate Anhydrous Allopurinol 1,5-DibromopentaneRelated products of tetrahydrofuran
You may like
-
4-Nitrophenylacetic acid 98%View Details -
104-03-0 4-Nitrophenylacetic acid 98%View Details
104-03-0 -
4-Nitrophenylaceticacid 104-03-0 95-99 %View Details
104-03-0 -
4-Nitrophenylacetic acid CAS 104-03-0View Details
104-03-0 -
4-Nitrophenylacetic acid 104-03-0 98%+View Details
104-03-0 -
(2-(4-nitrophenyl)acetic acid) NAA 104-03-0 98%+View Details
104-03-0 -
p-Nitrophenylacetic Acid pure CAS 104-03-0View Details
104-03-0 -
4-Nitrophenylacetic Acid CAS 104-03-0View Details
104-03-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.