4-Nitrobenzaldehyde

Chemical properties

YELLOW TO BROWN CRYSTALLINE POWDER

The Uses of 4-Nitrobenzaldehyde

4-Nitrobenzaldehyde is a benzaldehyde with a nitro group in the para position. It is used as a reagent in decarboxylative aldol reactions catalyzed by lipases and proteases in organic co-solvent mixtures. It was also used in the preparation of homoallylic alcohols. It was used to develop and evaluate a series of tripeptide organocatalysts.

Definition

ChEBI: 4-nitrobenzaldehyde is a C-nitro compound that is benzaldehyde substituted at the para-position with a nitro group. It is a C-nitro compound and a member of benzaldehydes.

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 252, 1956 DOI: 10.1021/ja01582a072
Tetrahedron Letters, 28, p. 4285, 1987 DOI: 10.1016/S0040-4039(00)96486-4

Description

4-Nitrobenzaldehyde is an organic aromatic compound containing a nitro group para-substituted to an aldehyde. This compound is a compound that exhibits high self-heating rates and can reach pressures exceeding 170 bar during decomposition.

Purification Methods

Purify it as for m-nitrobenzaldehyde above. [Beilstein 7 IV 589.]