3-(4-Hydroxyphenyl)propionic acid

Synonym(s):3-(p-Hydroxyphenyl)propionic acid;Phloretic acid

CAS NO.：501-97-3
Empirical Formula: C9H10O3
Molecular Weight: 166.17
MDL number: MFCD00002778
EINECS: 207-931-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-20 11:41:24

3-(4-Hydroxyphenyl)propionic acid Structural

What is 3-(4-Hydroxyphenyl)propionic acid?

Chemical properties

Pale-Yellow Crystals

The Uses of 3-(4-Hydroxyphenyl)propionic acid

3-(4-Hydroxyphenyl)propionic acid is uses as pharmaceutical intermediates,it is also used as a sensitive fluorogenic substrate for oxidases such as horseradish peroxidase.

The Uses of 3-(4-Hydroxyphenyl)propionic acid

Antioxidant

What are the applications of Application

3-(4-Hydroxyphenyl)propionic Acid is a potential antioxidant

Definition

ChEBI: A hydroxy monocarboxylic acid consisting of propionic acid having a 4-hydroxyphenyl group at the 3-position.

Purification Methods

3-p-Hydroxyphenylpropionic acid (phloretic acid) [501-97-3] M 166.2, m 129-130o, 131 -1 3 3o, pKEst(1)~4.7, pKEst(2)~10.1. Crystallise phloretic acid from ether or H2O. [Beilstein 10 IV 631.]

Properties of 3-(4-Hydroxyphenyl)propionic acid

Melting point:	129-131 °C(lit.)
Boiling point:	254.38°C (rough estimate)
Density	1.1708 (rough estimate)
refractive index	1.5286 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	4.74±0.10(Predicted)
form	Powder or Granules
color	Off-white to beige
Water Solubility	slightly soluble
BRN	2209841
CAS DataBase Reference	501-97-3(CAS DataBase Reference)
NIST Chemistry Reference	4-Hydroxyphenylpropionic acid(501-97-3)
EPA Substance Registry System	Benzenepropanoic acid, 4-hydroxy- (501-97-3)

Safety information for 3-(4-Hydroxyphenyl)propionic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.