4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Synonym(s):p-Nitrophenyl α-D-galactopyranoside

CAS NO.：7493-95-0
Empirical Formula: C12H15NO8
Molecular Weight: 301.25
MDL number: MFCD00065050
EINECS: 231-343-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 13:28:54

4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE Structural

What is 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE?

Chemical properties

Off-White Crystalline Solid

The Uses of 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

p-Nitrophenyl α-D-Galactopyranoside (cas# 7493-95-0) is a compound useful in organic synthesis.

What are the applications of Application

4-Nitrophenyl α-D-galactopyranoside is a chromogenic substrate used to detect hydrolase enzymes

Definition

ChEBI: An alpha-D-galactopyranoside having a 4-nitrophenyl substituent at the anomeric position.

Purification Methods

Purify 4-nitrophenyl--D-galactopyranoside by recrystallisation from H2O or aqueous EtOH. The monohydrate has m 85o which resolidifies and melts again at 151-152o (the hemihydrate), then resolidifies again and melts at 173o to give the anhydrous form. Drying the monohydrate at 60o yields the hemihydrate, and drying at 100o gives the anhydrous compound. The tetraacetate has m 147o after drying at 100o. [Jermyn Aust J Chem 15 569 1962, Helfreich & Jung Justus Liebigs Ann Chem 589 77 1954.] It is a substrate for galactosidase [Dangelmaier & Holmsen Anal Biochem 104 182 1980]. [Beilstein 17/7 V 55.]

Properties of 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Melting point:	166-169 °C
Boiling point:	582.2±50.0 °C(Predicted)
Density	1.599±0.06 g/cm3(Predicted)
refractive index	239 ° (C=1, H2O)
storage temp.	-20°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
pka	12.55±0.70(Predicted)
color	White to Off-White
BRN	92214
CAS DataBase Reference	7493-95-0(CAS DataBase Reference)

Safety information for 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.