4-NITROPHENYL-BETA-D-GLUCURONIDE

Synonym(s):p-Nitrophenyl-β-D-glucopyranosiduronic Acid;p-Nitrophenyl-β-D-glucuronide - CAS 10344-94-2 - Calbiochem;4-Nitrophenyl β-D-glucuronide;4-Nitrophenyl-β-D-glucopyranosiduronic acid;PNPG

CAS NO.：10344-94-2
Empirical Formula: C12H13NO9
Molecular Weight: 315.23
MDL number: MFCD00036210
EINECS: 233-753-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

4-NITROPHENYL-BETA-D-GLUCURONIDE Structural

What is 4-NITROPHENYL-BETA-D-GLUCURONIDE?

Chemical properties

Crystalline Solid

The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.

The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

What are the applications of Application

p-Nitrophenyl-β-D-glucuronide is a chromogenic substrate

Definition

ChEBI: A beta-D-glucosiduronic acid having a 4-nitrophenyl substituent at the anomeric position.

General Description

Chromogenic substrate for β-glucuronidase (K_m = ~0.22 mM).

Properties of 4-NITROPHENYL-BETA-D-GLUCURONIDE

Melting point:	93°C
Boiling point:	644.4±55.0 °C(Predicted)
Density	1.731±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	H₂O: 0.1 g/mL, clear, faintly yellow
form	Liquid
pka	2.69±0.70(Predicted)
color	Clear colorless to light yellow
optical activity	[α]20/D 102±3°, c = 1% in ethanol
Water Solubility	Water : 250 mg/mL (793.07 mM; Need ultrasonic)
BRN	1438576
CAS DataBase Reference	10344-94-2(CAS DataBase Reference)

Safety information for 4-NITROPHENYL-BETA-D-GLUCURONIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.