4-NITROPHENYL-BETA-D-GLUCURONIDE
Synonym(s):p-Nitrophenyl-β-D-glucopyranosiduronic Acid;p-Nitrophenyl-β-D-glucuronide - CAS 10344-94-2 - Calbiochem;4-Nitrophenyl β-D-glucuronide;4-Nitrophenyl-β-D -glucopyranosiduronic acid;PNPG
- CAS NO.：10344-94-2
- Empirical Formula: C12H13NO9
- Molecular Weight: 315.23
- MDL number: MFCD00036210
- EINECS: 233-753-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:20
What is 4-NITROPHENYL-BETA-D-GLUCURONIDE?
Chemical properties
Crystalline Solid
The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE
4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.
The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE
4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.
What are the applications of Application
p-Nitrophenyl-β-D-glucuronide is a chromogenic substrate
Definition
ChEBI: A beta-D-glucosiduronic acid having a 4-nitrophenyl substituent at the anomeric position.
General Description
Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).
Properties of 4-NITROPHENYL-BETA-D-GLUCURONIDE
| Melting point: | 93°C |
| Boiling point: | 644.4±55.0 °C(Predicted) |
| Density | 1.731±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: 0.1 g/mL, clear, faintly yellow |
| form | Liquid |
| pka | 2.69±0.70(Predicted) |
| color | Clear colorless to light yellow |
| optical activity | [α]20/D 102±3°, c = 1% in ethanol |
| Water Solubility | Water : 250 mg/mL (793.07 mM; Need ultrasonic) |
| BRN | 1438576 |
| CAS DataBase Reference | 10344-94-2(CAS DataBase Reference) |
Safety information for 4-NITROPHENYL-BETA-D-GLUCURONIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-NITROPHENYL-BETA-D-GLUCURONIDE
| InChIKey | QSUILVWOWLUOEU-GOVZDWNOSA-N |
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