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HomeProduct name list4-NITROPHENYL-BETA-D-GLUCURONIDE

4-NITROPHENYL-BETA-D-GLUCURONIDE

Synonym(s):p-Nitrophenyl-β-D-glucopyranosiduronic Acid;p-Nitrophenyl-β-D-glucuronide - CAS 10344-94-2 - Calbiochem;4-Nitrophenyl β-D-glucuronide;4-Nitrophenyl-β-D-glucopyranosiduronic acid;PNPG

  • CAS NO.:10344-94-2
  • Empirical Formula: C12H13NO9
  • Molecular Weight: 315.23
  • MDL number: MFCD00036210
  • EINECS: 233-753-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
4-NITROPHENYL-BETA-D-GLUCURONIDE Structural

What is 4-NITROPHENYL-BETA-D-GLUCURONIDE?

Chemical properties

Crystalline Solid

The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.

The Uses of 4-NITROPHENYL-BETA-D-GLUCURONIDE

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

What are the applications of Application

p-Nitrophenyl-β-D-glucuronide is a chromogenic substrate

Definition

ChEBI: A beta-D-glucosiduronic acid having a 4-nitrophenyl substituent at the anomeric position.

General Description

Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).

Properties of 4-NITROPHENYL-BETA-D-GLUCURONIDE

Melting point: 93°C
Boiling point: 644.4±55.0 °C(Predicted)
Density  1.731±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  H2O: 0.1 g/mL, clear, faintly yellow
form  Liquid
pka 2.69±0.70(Predicted)
color  Clear colorless to light yellow
optical activity [α]20/D 102±3°, c = 1% in ethanol
Water Solubility  Water : 250 mg/mL (793.07 mM; Need ultrasonic)
BRN  1438576
CAS DataBase Reference 10344-94-2(CAS DataBase Reference)

Safety information for 4-NITROPHENYL-BETA-D-GLUCURONIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-NITROPHENYL-BETA-D-GLUCURONIDE

InChIKey QSUILVWOWLUOEU-GOVZDWNOSA-N

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