4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
Synonym(s):p-Nitrophenyl α-D -glucopyranoside;p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem
- CAS NO.：3767-28-0
- Empirical Formula: C12H15NO8
- Molecular Weight: 301.25
- MDL number: MFCD00064088
- EINECS: 223-189-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-03 12:01:51
What is 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE?
Chemical properties
White Crystals
The Uses of 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
Substrate for a-glucosidase inhibitor
The Uses of 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
p-Nitrophenyl α-D-Glucopyranoside is a substrate for α-glucosidase inhibitor.
What are the applications of Application
4-Nitrophenyl-α-D- glucopyranoside is a useful chromogenic substrate for α-D-glucosidase
Definition
ChEBI: An alpha-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.
Purification Methods
Purify 4-nitrophenyl--D-glucopyranoside by recrystallisation from H2O, MeOH or EtOH. [Jermyn Aust J Chem 7 202 1954, Montgomery et al. J Am Chem Soc 64 690 1942.] It is a chromogenic substrate from -glucosidases [Oliviera et al. Anal Biochem 1 1 3 1881981], and is a C5227substrate for glucansucrases [Binder & Robyt Carbohydr Research 124 2871983]. [Beilstein 17/7 V 53.]
Properties of 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
| Melting point: | 210-216 °C |
| Boiling point: | 442.39°C (rough estimate) |
| Density | 1.3709 (rough estimate) |
| refractive index | 218.5 ° (C=0.5, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.3 mg/ml |
| form | Crystalline Powder |
| pka | 12.55±0.70(Predicted) |
| color | Off-white to light yellow |
| Water Solubility | Soluble in water, warm ethanol and methanol. |
| BRN | 92212 |
| CAS DataBase Reference | 3767-28-0(CAS DataBase Reference) |
Safety information for 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P330:Rinse mouth. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
| InChIKey | IFBHRQDFSNCLOZ-ZIQFBCGOSA-N |
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