4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID
- CAS NO.:55894-52-5
- Empirical Formula: C15H19NO6
- Molecular Weight: 309.31
- MDL number: MFCD00132973
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID?
Description
NOBA (55894-52-5) is a chromogenic substrate for phospholipases such as PLA2. Read absorbance at 425 nm.
The Uses of 4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID
4-Nitro-3-[(1-oxooctyl)oxy]benzoic acid is used to acrylate ε-amino groups of Lysine (L468895) in order to immobilize phospholipase A2 in snake venom.
References
1) Cho & Kezdy (1991), Chromogenic Substrates and assay of phospholipases A2; Methods Enzymol., 197 75 2) Petrovic et al. (2001), A simple assay for a human serum phospholipase A2 that is associated with high density lipoproteins; J. Lipid Res., 42 1706 3) Bonfim et al. (2008), Structural and functional characterization of myotoxin, Cr-IV 1, a phospholipase A2 D49 from the venom of the snake Calloselasma rhodostoma; Biologicals, 36 168
Properties of 4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID
Melting point: | 146 - 148°C |
storage temp. | RT |
solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). |
form | Off-white solid. |
color | White |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months |
Safety information for 4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID
Computed Descriptors for 4-NITRO-3-(OCTANOYLOXY)BENZOIC ACID
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