PHOSPHATIDYLETHANOL

CAS NO.：765260-45-5
Empirical Formula: C41H79O9P
Molecular Weight: 747.03
MDL number: MFCD00211162
Update Date: 2023-04-23 13:52:06

What is PHOSPHATIDYLETHANOL?

Description

Phosphatidlyethanol is an endogenous metabolite of phosphatidylcholine. Phospholipase D converts phosphatidylcholine to phosphatidylethanol in the presence of ethanol. This reaction is the basis of a sensitive and selective assay for PLD activity in intact cells for which this product may be used as a chromatographic standard.

References

1) Kobayashi et al. (1987), Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D; J. Neurochem., 48 1597 2) Liscovith et al. (1989), Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells. Evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C; J. Biol. Chem., 264 1450 3) Pai et al. (1988), Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes; J. Biol. Chem., 263 12472

Properties of PHOSPHATIDYLETHANOL

storage temp.	-20°
solubility	Soluble in Chloroform (up to 10 mg/ml).
form	Viscous oil / waxy solid
Stability:	Stable for 2 years from date of purchase as supplied. Phosphatidylethanol is subject to oxidation and must be protected from exposure to air. Solutions in chloroform may be stored at -20° for up to 3 months.