PHOSPHATIDYLETHANOL
- CAS NO.：765260-45-5
- Empirical Formula: C41H79O9P
- Molecular Weight: 747.03
- MDL number: MFCD00211162
- Update Date: 2023-04-23 13:52:06
What is PHOSPHATIDYLETHANOL?
Description
Phosphatidlyethanol is an endogenous metabolite of phosphatidylcholine. Phospholipase D converts phosphatidylcholine to phosphatidylethanol in the presence of ethanol. This reaction is the basis of a sensitive and selective assay for PLD activity in intact cells for which this product may be used as a chromatographic standard.
References
1) Kobayashi et al. (1987), Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D; J. Neurochem., 48 1597 2) Liscovith et al. (1989), Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells. Evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C; J. Biol. Chem., 264 1450 3) Pai et al. (1988), Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes; J. Biol. Chem., 263 12472
Properties of PHOSPHATIDYLETHANOL
| storage temp. | -20° |
| solubility | Soluble in Chloroform (up to 10 mg/ml). |
| form | Viscous oil / waxy solid |
| Stability: | Stable for 2 years from date of purchase as supplied. Phosphatidylethanol is subject to oxidation and must be protected from exposure to air. Solutions in chloroform may be stored at -20° for up to 3 months. |
Safety information for PHOSPHATIDYLETHANOL
Computed Descriptors for PHOSPHATIDYLETHANOL
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