4-(N-Maleimido)benzophenone

Synonym(s):Benzophenone-4-maleimide

CAS NO.：92944-71-3
Empirical Formula: C17H11NO3
Molecular Weight: 277.27
MDL number: MFCD00079465
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-14 08:28:44

What is 4-(N-Maleimido)benzophenone?

Chemical properties

Light Beige Solid

The Uses of 4-(N-Maleimido)benzophenone

4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols

The Uses of 4-(N-Maleimido)benzophenone

Maleimide-containing benzophenone as photoinitiator

The Uses of 4-(N-Maleimido)benzophenone

A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to

What are the applications of Application

4-(Maleimido)benzophenone is a benzophenone-based, sulfhydryl-reactive photoreactive crosslinker

Properties of 4-(N-Maleimido)benzophenone

Melting point:	155-157°C
Boiling point:	472.9±28.0 °C(Predicted)
Density	1.330±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	chloroform: 50 mg/mL
form	Solid
pka	-3.80±0.20(Predicted)
color	Light Beige

Safety information for 4-(N-Maleimido)benzophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.