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HomeProduct name list4-(N-Maleimido)benzophenone

4-(N-Maleimido)benzophenone

Synonym(s):Benzophenone-4-maleimide

4-(N-Maleimido)benzophenone Structural

What is 4-(N-Maleimido)benzophenone?

Chemical properties

Light Beige Solid

The Uses of 4-(N-Maleimido)benzophenone

4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols

The Uses of 4-(N-Maleimido)benzophenone

Maleimide-containing benzophenone as photoinitiator

The Uses of 4-(N-Maleimido)benzophenone

A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to

What are the applications of Application

4-(Maleimido)benzophenone is a benzophenone-based, sulfhydryl-reactive photoreactive crosslinker

Properties of 4-(N-Maleimido)benzophenone

Melting point: 155-157°C
Boiling point: 472.9±28.0 °C(Predicted)
Density  1.330±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL
form  Solid
pka -3.80±0.20(Predicted)
color  Light Beige

Safety information for 4-(N-Maleimido)benzophenone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-(N-Maleimido)benzophenone

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