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HomeProduct name listN-Succinimidyl maleimidoacetate

N-Succinimidyl maleimidoacetate

N-Succinimidyl maleimidoacetate Structural

What is N-Succinimidyl maleimidoacetate?

Chemical properties

White Crystalline Solid

The Uses of N-Succinimidyl maleimidoacetate

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates

The Uses of N-Succinimidyl maleimidoacetate

Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.

The Uses of N-Succinimidyl maleimidoacetate

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates.

What are the applications of Application

Maleimidoacetic Acid N-Hydroxysuccinimide Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker

Properties of N-Succinimidyl maleimidoacetate

Melting point: 174-175°C
Boiling point: 430.1±47.0 °C(Predicted)
Density  1.63±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat
form  Solid
pka -2.69±0.20(Predicted)
color  White to Off-White
InChI InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2
CAS DataBase Reference 55750-61-3

Safety information for N-Succinimidyl maleimidoacetate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Succinimidyl maleimidoacetate

InChIKey TYKASZBHFXBROF-UHFFFAOYSA-N
SMILES N1(CC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O

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