N-Succinimidyl maleimidoacetate

CAS NO.：55750-61-3
Empirical Formula: C10H8N2O6
Molecular Weight: 252.18
MDL number: MFCD00133523
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-20 16:43:00

What is N-Succinimidyl maleimidoacetate?

Chemical properties

White Crystalline Solid

The Uses of N-Succinimidyl maleimidoacetate

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates

The Uses of N-Succinimidyl maleimidoacetate

Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.

The Uses of N-Succinimidyl maleimidoacetate

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates.

What are the applications of Application

Maleimidoacetic Acid N-Hydroxysuccinimide Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker

Properties of N-Succinimidyl maleimidoacetate

Melting point:	174-175°C
Boiling point:	430.1±47.0 °C(Predicted)
Density	1.63±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat
form	Solid
pka	-2.69±0.20(Predicted)
color	White to Off-White
InChI	InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2
CAS DataBase Reference	55750-61-3

Safety information for N-Succinimidyl maleimidoacetate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.