N-Succinimidyl maleimidoacetate
- CAS NO.:55750-61-3
- Empirical Formula: C10H8N2O6
- Molecular Weight: 252.18
- MDL number: MFCD00133523
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-20 16:43:00
What is N-Succinimidyl maleimidoacetate?
Chemical properties
White Crystalline Solid
The Uses of N-Succinimidyl maleimidoacetate
A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates
The Uses of N-Succinimidyl maleimidoacetate
Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.
The Uses of N-Succinimidyl maleimidoacetate
A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates.
What are the applications of Application
Maleimidoacetic Acid N-Hydroxysuccinimide Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker
Properties of N-Succinimidyl maleimidoacetate
Melting point: | 174-175°C |
Boiling point: | 430.1±47.0 °C(Predicted) |
Density | 1.63±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat |
form | Solid |
pka | -2.69±0.20(Predicted) |
color | White to Off-White |
InChI | InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2 |
CAS DataBase Reference | 55750-61-3 |
Safety information for N-Succinimidyl maleimidoacetate
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Succinimidyl maleimidoacetate
InChIKey | TYKASZBHFXBROF-UHFFFAOYSA-N |
SMILES | N1(CC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O |
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