4-Methylpiperidine
Synonym(s):γ-Pipecoline;4-Methylpiperidine;4-Methylpiperidine solution;4-Pipecoline
- CAS NO.：626-58-4
- Empirical Formula: C6H13N
- Molecular Weight: 99.17
- MDL number: MFCD00006005
- EINECS: 210-954-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is 4-Methylpiperidine?
Chemical properties
clear slightly yellow liquid
The Uses of 4-Methylpiperidine
4-Methylpiperidine is used as a catalyst in the synthesis of stilbene derivatives as anti-malarial agents. It also serves as an anti-corrosive compound for iron.
The Uses of 4-Methylpiperidine
4-Methylpiperidine acts as a catalyst in the preparation of stilbene derivatives. It is used as an anti-corrosive compound for iron. It is also used in the synthesis of peptides to remove or deprotection of 9-fluorenylmethyloxycarbonyl (Fmoc) groups.
Purification Methods
Purify it via the hydrochloride (m 189o). It is freed from 3-methylpyridine by zone melting. The hydrobromide has m 173o(from butanone/*C6H6). [Beilstein 20 III/IV 1511, 20/4 V 116.]
Properties of 4-Methylpiperidine
| Melting point: | 4-5 °C |
| Boiling point: | 124 °C(lit.) |
| Density | 0.838 g/mL at 25 °C(lit.) |
| vapor pressure | 16 hPa (20 °C) |
| refractive index | n |
| Flash point: | 45 °F |
| storage temp. | Flammables area |
| solubility | Chloroform |
| form | Liquid |
| pka | pK1:11.23(+1) (25°C,μ=0.5) |
| Specific Gravity | 0.838 |
| color | Clear slightly yellow |
| PH | 13 (100g/l, H2O, 20℃) |
| Water Solubility | miscible |
| BRN | 1083 |
| CAS DataBase Reference | 626-58-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Piperidine, 4-methyl-(626-58-4) |
| EPA Substance Registry System | Piperidine, 4-methyl- (626-58-4) |
Safety information for 4-Methylpiperidine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Methylpiperidine
4-Methylpiperidine manufacturer
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