4-Methylphenylsulfonylurea
- CAS NO.：1694-06-0
- Empirical Formula: C8H10N2O3S
- Molecular Weight: 214.24
- MDL number: MFCD00196522
- EINECS: 216-900-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-19 17:35:41
What is 4-Methylphenylsulfonylurea?
Chemical properties
white crystalline powder
The Uses of 4-Methylphenylsulfonylurea
4-Methylphenylsulfonylurea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.
The Uses of 4-Methylphenylsulfonylurea
4-Methylphenylsulfonylurea can be used as pharmaceutical intermediate.
The Uses of 4-Methylphenylsulfonylurea
N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.
Properties of 4-Methylphenylsulfonylurea
| Melting point: | 196-198 °C |
| Density | 1.3844 (rough estimate) |
| refractive index | 1.5690 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 5.07±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 777.9mg/L(37 ºC) |
| CAS DataBase Reference | 1694-06-0(CAS DataBase Reference) |
Safety information for 4-Methylphenylsulfonylurea
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H304:Aspiration hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P280:Wear protective gloves/protective clothing/eye protection/face protection. P331:Do NOT induce vomiting. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 4-Methylphenylsulfonylurea
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