4-Methylbenzenesulfonhydrazide
Synonym(s):TSH;Tosylhydrazide;p-Toluenesulfonhydrazide;p-Toluenesulfonic acid hydrazide;p-Toluenesulfonyl hydrazide
- CAS NO.：1576-35-8
- Empirical Formula: C7H10N2O2S
- Molecular Weight: 186.23
- MDL number: MFCD00007588
- EINECS: 216-407-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 4-Methylbenzenesulfonhydrazide?
Chemical properties
white to off-white powder
The Uses of 4-Methylbenzenesulfonhydrazide
4-Methylbenzenesulfonhydrazide was widely used reagent for the preparation of tosylhydrazones.
The Uses of 4-Methylbenzenesulfonhydrazide
p-Toluenesulfonyl hydrazide is used as a reagent for the preparation of tosylhydrazones. It was used to prepare dipyrazolo[1,5-a:4?,3?-c]pyridines and 1,2,3-selenadiazole derivatives.
Flammability and Explosibility
Not classified
Purification Methods
Dissolve the hydrazide in hot MeOH (~1g/4mL), filter through Celite and precipitate the material by adding 2-2.5 volumes of distilled H2O. Dry it in air or in a vacuum. [Fiedman et al. Org Synth Coll Vol V 1055 1973, Beilstein 11 II 66.]
Properties of 4-Methylbenzenesulfonhydrazide
| Melting point: | 103-108 °C(lit.) |
| Boiling point: | 340.5±35.0 °C(Predicted) |
| Density | 1.42g/cm3 |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.5400 (estimate) |
| Flash point: | 60°C |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | 5g/l |
| form | Powder |
| pka | 9.39±0.10(Predicted) |
| color | White or off-white to slightly grayish |
| Water Solubility | 5 g/L (15 ºC) |
| Sensitive | Moisture Sensitive |
| BRN | 610130 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 1576-35-8(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenesulfonic acid, 4-methyl-, hydrazide (1576-35-8) |
Safety information for 4-Methylbenzenesulfonhydrazide
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H290:Corrosive to Metals |
| Precautionary Statement Codes |
P234:Keep only in original container. P390:Absorb spillage to prevent material damage. |
Computed Descriptors for 4-Methylbenzenesulfonhydrazide
| InChIKey | ICGLPKIVTVWCFT-UHFFFAOYSA-N |
4-Methylbenzenesulfonhydrazide manufacturer
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
![1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene](https://img.chemicalbook.in/CAS2/GIF/159276-58-1.gif)
![PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE](https://img.chemicalbook.in/CAS/GIF/184177-81-9.gif)
![2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,](https://img.chemicalbook.in/CAS/GIF/184177-83-1.gif)
![Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI)](https://img.chemicalbook.in/CAS/20200331/GIF/183871-34-3.gif)
You may like
-
1576-35-8 98%View Details
1576-35-8 -
Tosyl Hydrazine 99%View Details
1576-35-8 -
4-Toluenesulfonylhydrazide 1576-35-8 98%View Details
1576-35-8 -
1576-35-8 4-Toluenesulfonylhydrazide 98%View Details
1576-35-8 -
1576-35-8 98%View Details
1576-35-8 -
p-Toluenesulfonyl hydrazide, 97% CAS 1576-35-8View Details
1576-35-8 -
p-Toluenesulfonylhydrazide 95% CAS 1576-35-8View Details
1576-35-8 -
p-Toluenesulfonyl hydrazide CAS 1576-35-8View Details
1576-35-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.