4'-Methylbiphenyl-2-carboxylic acid
- CAS NO.：7148-03-0
- Empirical Formula: C14H12O2
- Molecular Weight: 212.24
- MDL number: MFCD00045826
- EINECS: 230-462-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is 4'-Methylbiphenyl-2-carboxylic acid?
Chemical properties
Light yellow solid
The Uses of 4'-Methylbiphenyl-2-carboxylic acid
4’-Methylbiphenyl-2-carboxylic Acid is used in the synthesis of angiotensin II receptor antagonists used as potent orally active antihypertensives.
General Description
4′-Methyl-2-biphenylcarboxylic acid (4′-Methyl-bi-phenyl-2-carboxyl-ic acid) can be synthesized by reacting 4′-methylbiphenyl-2-carbonitrile with methanol and 30% NaOH solution. Its crystal structure has been characterized by the centrosymmetric hydrogen-bonded dimers.
Purification Methods
Crystallise the acid from toluene or *C6H6 (m 147-148o). [Beilstein 9 H 677, 9 IV 2523.]
Properties of 4'-Methylbiphenyl-2-carboxylic acid
| Melting point: | 146-148°C |
| Boiling point: | 354.5±11.0 °C(Predicted) |
| Density | 1.156±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| form | Solid |
| pka | 3.90±0.36(Predicted) |
| color | White |
| CAS DataBase Reference | 7148-03-0(CAS DataBase Reference) |
| EPA Substance Registry System | [1,1'-Biphenyl]-2-carboxylic acid, 4'-methyl- (7148-03-0) |
Safety information for 4'-Methylbiphenyl-2-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4'-Methylbiphenyl-2-carboxylic acid
4'-Methylbiphenyl-2-carboxylic acid manufacturer
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
2Y
Phone:+91-9966658228
Whatsapp: +91- 9966658228
product: 7148-03-0 2-(p-Tolyl)-benzoic acid 99%
Viyash Life Sciences Pvt Ltd
1Y
Phone:+91-4023635052
product: 4'-Methylbiphenyl-2-carboxylic acid 98%
Lakshmi Farmachem
1Y
Phone:+91-9550886476
Whatsapp: +91-9550886476
product: 4'-Methylbiphenyl-2-carboxylic acid 98%
HYPERSYNTH LIFE SCIENCES
1Y
Phone:+91-9989233308
Whatsapp: +91-9989233308
product: 7148-03-0 4'-Methylbiphenyl-2-carboxylic acid 99%
A.J Chemicals
New Delhi
Phone:91-9810153283
Whatsapp: 91-9810153283
product: 4'-Methylbiphenyl-2-carboxylic acid
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
7148-03-0 2-(p-Tolyl)-benzoic acid 99%View Details
7148-03-0 -
7148-03-0 98%View Details
7148-03-0 -
4'-Methylbiphenyl-2-carboxylic acid 98%View Details
7148-03-0 -
4'-Methylbiphenyl-2-carboxylic acid 98%View Details -
7148-03-0 4'-Methylbiphenyl-2-carboxylic acid 99%View Details
7148-03-0 -
2-(p-Tolyl)benzoic Acid CAS 7148-03-0View Details
7148-03-0 -
118753-70-1 98+View Details
118753-70-1 -
733039-20-8 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 98+View Details
733039-20-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.