4'-Methylbiphenyl-2-carboxylic acid
- CAS NO.：7148-03-0
- Empirical Formula: C14H12O2
- Molecular Weight: 212.24
- MDL number: MFCD00045826
- EINECS: 230-462-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:28:00
What is 4'-Methylbiphenyl-2-carboxylic acid?
Chemical properties
Light yellow solid
The Uses of 4'-Methylbiphenyl-2-carboxylic acid
4’-Methylbiphenyl-2-carboxylic Acid is used in the synthesis of angiotensin II receptor antagonists used as potent orally active antihypertensives.
General Description
4′-Methyl-2-biphenylcarboxylic acid (4′-Methyl-bi-phenyl-2-carboxyl-ic acid) can be synthesized by reacting 4′-methylbiphenyl-2-carbonitrile with methanol and 30% NaOH solution. Its crystal structure has been characterized by the centrosymmetric hydrogen-bonded dimers.
Purification Methods
Crystallise the acid from toluene or *C6H6 (m 147-148o). [Beilstein 9 H 677, 9 IV 2523.]
Properties of 4'-Methylbiphenyl-2-carboxylic acid
| Melting point: | 146-148°C |
| Boiling point: | 354.5±11.0 °C(Predicted) |
| Density | 1.156±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| form | Solid |
| pka | 3.90±0.36(Predicted) |
| color | White |
| CAS DataBase Reference | 7148-03-0(CAS DataBase Reference) |
| EPA Substance Registry System | [1,1'-Biphenyl]-2-carboxylic acid, 4'-methyl- (7148-03-0) |
Safety information for 4'-Methylbiphenyl-2-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4'-Methylbiphenyl-2-carboxylic acid
4'-Methylbiphenyl-2-carboxylic acid manufacturer
A.J Chemicals
New Delhi
Phone:91-9810153283
Whatsapp: 91-9810153283
product: 4'-Methylbiphenyl-2-carboxylic acid
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