4-Formylbenzoic acid

Synonym(s):4-Carboxybenzaldehyde;4-Formylbenzoic acid, 4-Carboxybenzaldehyde;Benzaldehyde-4-carboxylic acid;Terephthalaldehydic acid

CAS NO.：619-66-9
Empirical Formula: C8H6O3
Molecular Weight: 150.13
MDL number: MFCD00006951
EINECS: 210-607-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 4-Formylbenzoic acid?

Description

4-Formylbenzoic acid, also known as 4-Carboxybenzaldehyde, is a white crystalline powder with a molecular formula of C8H5O3. It is insoluble in water but can be dissolved in DMF. This compound has the ability to undergo esterification reactions and alcohol-aldehyde condensation reactions with alcohols. 4-Formylbenzoic acid is a metabolite of aldehydes. It is an important intermediate for organic synthesis, widely used in medicine, pesticides, coatings, liquid crystal raw materials, polymer materials and perfume raw materials.

Chemical properties

Yellowish fine crystalline powder

The Uses of 4-Formylbenzoic acid

4-Formylbenzoic acid is usually used as reagent during esterification of 2,2,6,6-tetramethyl-4-oxopiperidinyl-1-oxyl to yield 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl 4-formylbenzoate.

The Uses of 4-Formylbenzoic acid

4-Carboxybenzaldehyde is an important intermediate in the synthesis of terepthalic acid. It has been used as reagent during esterification of 2,2,6,6-tetramethyl-4-oxopiperidinyl-1-oxyl to yield 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl 4-formylbenzoate.

Definition

ChEBI: 4-formylbenzoic acid is a member of the class of benzoic acids that is benzoic acid substituted by a formyl group at position 4. It has a role as a plant metabolite. It is a member of benzaldehydes, a member of benzoic acids and a monocarboxylic acid. It is a conjugate acid of a 4-formylbenzoate.

General Description

4-Formylbenzoic acid is an important intermediate in the synthesis of terepthalic acid. It reacts with barium carbonate to yield two-dimensional barium(II) coordination polymer.

Properties of 4-Formylbenzoic acid

Melting point:	247 °C(lit.)
Boiling point:	231.65°C (rough estimate)
Density	1.2645 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Store below +30°C.
solubility	DMSO
pka	3.77(at 25℃)
form	Fine Crystalline Powder
color	Yellow
PH	3.5 (1g/l, H2O, 20℃)
Water Solubility	Soluble in water, methanol, DMSO, ether, and chloroform.
Sensitive	Air Sensitive
λmax	298nm(Hexane)(lit.)
BRN	471734
CAS DataBase Reference	619-66-9(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 4-formyl-(619-66-9)
EPA Substance Registry System	Benzoic acid, 4-formyl- (619-66-9)

Safety information for 4-Formylbenzoic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.