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HomeProduct name list4-MALEIMIDO-TEMPO

4-MALEIMIDO-TEMPO

Synonym(s):4-Maleimido-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical

4-MALEIMIDO-TEMPO Structural

What is 4-MALEIMIDO-TEMPO?

Chemical properties

Red-Orange Solid

The Uses of 4-MALEIMIDO-TEMPO

4-Maleimido-TEMPO (4-Maleimido-2,2,6,6,-tetramethylpiperidinooxyl) was employed as spin label to investigate the influence of bile salts on the intact rat mitochondrial membranes by electron paramagnetic resonance spectroscopy (EPR). It may be employed as spin label for the labeling of erythrocyte membranes to investigate the interaction of quercetin with erythrocyte proteins by EPR spectra.

The Uses of 4-MALEIMIDO-TEMPO

A thiol specific spin label.

What are the applications of Application

N-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)maleimide is A thiol specific spin label

Definition

ChEBI: 4-maleimido-TEMPO is a member of the class of piperidines that is TEMPO carrying a maleimido group at position 4. It has a role as a radical scavenger and a spin label. It is a member of aminoxyls, a member of piperidines, a member of maleimides and a dicarboximide. It is functionally related to a TEMPO.

General Description

4-Maleimido-TEMPO, a water-soluble nitroxide radical, is commonly employed as spin probe. It has been reported to inhibit the survival of CHO cells at 1mM concentrations. It is widely employed maleimide spin label for EPR studies.

Biochem/physiol Actions

Spin label used to study fluidity of brain synaptosomal membranes, internal microviscosity of erythrocytes, and human high density lipoproteins.

Properties of 4-MALEIMIDO-TEMPO

Melting point: 91-94 °C
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  Orange to Dark Orange

Safety information for 4-MALEIMIDO-TEMPO

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-MALEIMIDO-TEMPO

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