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HomeProduct name list1,5-Dimethylhexylamine

1,5-Dimethylhexylamine

Synonym(s):1,5-Dimethylhexylamine;6-Methyl-2-heptylamine

  • CAS NO.:543-82-8
  • Empirical Formula: C8H19N
  • Molecular Weight: 129.24
  • MDL number: MFCD00008092
  • EINECS: 208-851-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-30 19:23:35
1,5-Dimethylhexylamine Structural

What is 1,5-Dimethylhexylamine?

Chemical properties

clear colorless to light yellow liquid with fishy smell.

The Uses of 1,5-Dimethylhexylamine

1,5-Dimethylhexylamine is an aliphatic secondary amine which shows leucine aminotransferase inhibition. 1,5-Dimethylhexylamine is used in the preparation of glycosyl β-amino acids with antitubercular activity.

The Uses of 1,5-Dimethylhexylamine

2-Amino-6-methylheptane can be used as:

  • A building block for the synthesis of n-type photoconductor, N,N′-bis(1,5-dimethylhexyl)-3,4:9,10-perylenebis (dicarbox-imide) (PDHEP).
  • A reagent in the synthesis of substituted pyrrolidones by reductive amination of levulinic acid using supported platinum catalyst.
  • A nucleophilic amine in the synthesis of unsymmetrical sulfamide by reacting with sulfamic acid salts and triphenylphosphine ditriflate.

What are the applications of Application

2-Amino-6-methylheptane is a aliphatic secondary amine.

What are the applications of Application

1,5-Dimethylhexylamine can be used as a local anesthetic and vasoconstrictor, and it is mainly used as an intermediate in the production of gastrointestinal antispasmodic drug octamylamine.

Preparation

1,5-Dimethylhexylamine was synthesized from 6-methyl-2-heptanone ([928-68-7]) by amination and catalytic hydrogenation.

Definition

ChEBI: Octodrine is an alkylamine.

Properties of 1,5-Dimethylhexylamine

Melting point: 25°C
Boiling point: 154-156 °C(lit.)
Density  0.767 g/mL at 25 °C(lit.)
refractive index  n20/D 1.422(lit.)
Flash point: 120 °F
storage temp.  Flammables area
solubility  DMSO (Slightly), Methanol (Slightly)
form  Liquid
pka pKa 10.28 ± 0.1(H2O,t =25±0.2,I<0.001) (Uncertain)
color  White to Off-White
Merck  14,6757
BRN  1209250
Stability: Hygroscopic
CAS DataBase Reference 543-82-8(CAS DataBase Reference)
NIST Chemistry Reference Octodrine(543-82-8)
EPA Substance Registry System 2-Heptanamine, 6-methyl- (543-82-8)

Safety information for 1,5-Dimethylhexylamine

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1,5-Dimethylhexylamine

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