1-Benzyl-4-hydroxypiperidine
Synonym(s):1-Benzyl-4-piperidinol
- CAS NO.:4727-72-4
- Empirical Formula: C12H17NO
- Molecular Weight: 191.27
- MDL number: MFCD00006503
- EINECS: 225-226-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 13:32:20
What is 1-Benzyl-4-hydroxypiperidine?
Chemical properties
WHITE TO YELLOWISH CRYSTALLINE POWDER
The Uses of 1-Benzyl-4-hydroxypiperidine
A piperidine based pesticide
The Uses of 1-Benzyl-4-hydroxypiperidine
1-Benzyl-4-hydroxypiperidine is the reactant for synthesis of: Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist1 Fatty acid amide hydrolase inhibitors PI3 kinase-alpha inhibitors Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors Urotensin-II receptor antagonists Rho kinase inhibitors.
The Uses of 1-Benzyl-4-hydroxypiperidine
1-Benzyl-4-hydroxypiperidine was used as an alternative molecule to study the ligand concentration attached to the epoxy-activated Sepharose 6B.
Synthesis Reference(s)
Journal of the American Chemical Society, 108, p. 3512, 1986 DOI: 10.1021/ja00272a059
Properties of 1-Benzyl-4-hydroxypiperidine
Melting point: | 61-63 °C(lit.) |
Boiling point: | 127-128 °C2 mm Hg(lit.) |
Density | 1.0096 (rough estimate) |
refractive index | 1.5212 (estimate) |
Flash point: | 121-123°C/0.7mm |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform, Methanol |
pka | 14.87±0.20(Predicted) |
form | Crystalline Powder |
color | White to yellow |
Sensitive | Hygroscopic |
BRN | 146118 |
CAS DataBase Reference | 4727-72-4(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Piperidinol, 1-(phenylmethyl)-(4727-72-4) |
Safety information for 1-Benzyl-4-hydroxypiperidine
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Benzyl-4-hydroxypiperidine
Abamectin manufacturer
SYNARTIS PHARMA PVT LTD
2Y
Phone:+91-9949688280
Whatsapp: +91- 9949688280
product: 4727-72-4 NLT-98%
JSK Chemicals
1Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 4727-72-4 1-Benzyl-4-hydroxypiperidine, 95% 99%
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 1-Benzylpiperidin-4-ol 98%
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Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride
Benzyl chloride
N-Benzyl-4-piperidone
Benzyl
Haloperidol
Diphenoxylate
Benzyl alcohol
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