3-Hydroxypiperidine
Synonym(s):3-Piperidinol
- CAS NO.：6859-99-0
- Empirical Formula: C5H11NO
- Molecular Weight: 101.15
- MDL number: MFCD00014591
- EINECS: 229-957-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-03 11:51:57
What is 3-Hydroxypiperidine?
Chemical properties
White to light yellow crystalline powder and lumps
The Uses of 3-Hydroxypiperidine
3-Hydroxypiperidine is usually used for Synthesis of unsymmetrical ureas,Synthesis of piperidine nucleoside analogs,Fluorination reactions,Synthesis of substituted pyridines.
What are the applications of Application
3-Hydroxypiperidine may be used to synthesize the following:
2-pyrrolidinone via oxidation with iodosylbenzene
1-[2,8-bis(trifluoromethyl)quinolin-4-yl]piperidin-3-ol via reaction with 4-bromoquinoline
Reactant for:
Synthesis of unsymmetrical ureas
Synthesis of piperidine nucleoside analogs
Fluorination reactions
Synthesis of substituted pyridines
General Description
3-Hydroxypiperidine can be obtained from the reduction of 3-hydroxypyridine.
Properties of 3-Hydroxypiperidine
| Melting point: | 57-61 °C |
| Boiling point: | 67-69 °C (2 mmHg) |
| Density | 1.016±0.06 g/cm3(Predicted) |
| Flash point: | >100°C |
| storage temp. | 2-8°C |
| solubility | ethanol: 0.1 g/mL, clear |
| form | Crystalline Powder and Lumps |
| pka | 14.91±0.20(Predicted) |
| color | White to light yellow |
| PH | 11.5-11.7 (H2O)Aqueous solution |
| Water Solubility | soluble |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 102696 |
| CAS DataBase Reference | 6859-99-0(CAS DataBase Reference) |
Safety information for 3-Hydroxypiperidine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. |
Computed Descriptors for 3-Hydroxypiperidine
| InChIKey | BIWOSRSKDCZIFM-UHFFFAOYSA-N |
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product: 6859-99-0 3-Hydroxypiperidine >98%
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