5-(4-Hydroxyphenyl)-2,4-imidazolidinedione
- CAS NO.:2420-17-9
- Empirical Formula: C9H8N2O3
- Molecular Weight: 192.17
- MDL number: MFCD00044002
- EINECS: 219-340-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is 5-(4-Hydroxyphenyl)-2,4-imidazolidinedione?
Flammability and Explosibility
Non flammable
Synthesis
Add 4.0 g of glyoxylic acid monohydrate (0.04 mol), 1.2 g of urea (0.02 mol), and 10 mL of 10% hydrochloric acid into the beaker. Stir evenly. After releasing the heat, pour it into a dropping funnel and set aside. Add 3.6 g (0.06 mol) of urea, 5.6 g (0.06 mol) of phenol, and 10% hydrochloric acid, and stir evenly in a three-necked flask. Heat to 90 ℃, slowly add the glyoxylic acid-urea mixture dropwise and control the dropping speed for about 4 hours. After the dropwise addition is completed, continue the heat preservation reaction for 2 hours to complete the reaction. Change the reaction device to a vacuum distillation device to recover excess phenol. After evaporating about 1/3 of the volume of the solution, cool to about 15°C to crystallize, filter, and use the filter cake. Wash with water 2 to 3 times until neutral and dry to obtain 5.8 g of white solid 5-(4-Hydroxyphenyl)-2,4-imidazolidinedione.
Properties of 5-(4-Hydroxyphenyl)-2,4-imidazolidinedione
Melting point: | >260°C |
Boiling point: | 273.7℃[at 101 325 Pa] |
Density | 1.408 |
vapor pressure | 0Pa at 25℃ |
storage temp. | Inert atmosphere,Room Temperature |
form | powder to crystal |
pka | 8.67±0.10(Predicted) |
color | White to Almost white |
Water Solubility | 1.29g/L at 20℃ |
InChI | InChI=1S/C9H8N2O3/c12-6-3-1-5(2-4-6)7-8(13)11-9(14)10-7/h1-4,7,12H,(H2,10,11,13,14) |
CAS DataBase Reference | 2420-17-9(CAS DataBase Reference) |
Safety information for 5-(4-Hydroxyphenyl)-2,4-imidazolidinedione
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P501:Dispose of contents/container to..… |
Computed Descriptors for 5-(4-Hydroxyphenyl)-2,4-imidazolidinedione
InChIKey | UMTNMIARZPDSDI-UHFFFAOYSA-N |
SMILES | C1(=O)NC(C2=CC=C(O)C=C2)C(=O)N1 |
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