4'-Hydroxyphenyl Carvedilol
Synonym(s):4′-Hydroxy carvedilol;4′-Hydroxyphenyl carvedilol;4′-OH carvedilol;4′OH-CVD;4-(2-(3-(9H-carbazol-4-yloxy)-2-hydroxypropylamino)ethoxy)-3-methoxyphenol
- CAS NO.:142227-49-4
- Empirical Formula: C24H26N2O5
- Molecular Weight: 422.47
- MDL number: MFCD04039561
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:03
What is 4'-Hydroxyphenyl Carvedilol?
Description
4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
Chemical properties
Off-White Solid
The Uses of 4'-Hydroxyphenyl Carvedilol
4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
The Uses of 4'-Hydroxyphenyl Carvedilol
A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.
The Uses of 4'-Hydroxyphenyl Carvedilol
An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.
What are the applications of Application
4′-Hydroxyphenyl Carvedilol is a multiple-action, neurohormonal antagonist
Definition
ChEBI: 4'-Hydroxyphenyl Carvedilol is a member of carbazoles.
Properties of 4'-Hydroxyphenyl Carvedilol
Melting point: | 163-165°C |
Boiling point: | 702.0±60.0 °C(Predicted) |
Density | 1.305±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 9.94±0.20(Predicted) |
color | White to Light Brown |
Safety information for 4'-Hydroxyphenyl Carvedilol
Computed Descriptors for 4'-Hydroxyphenyl Carvedilol
New Products
Tubulysin B Tubulysin A Tubulysin D Tubulysin E 2,2-Difluoropropylamine hydrochloride 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID tetrahydro-4-methyl-2H-pyran Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2,2-Difluoropropanol 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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