4-Hydroxyphenethyl alcohol
Synonym(s):2-(4-Hydroxyphenyl)ethanol;4-Hydroxyphenethyl alcohol;p-HPEA;Tyrosol
- CAS NO.:501-94-0
- Empirical Formula: C8H10O2
- Molecular Weight: 138.16
- MDL number: MFCD00002902
- EINECS: 207-930-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02

What is 4-Hydroxyphenethyl alcohol?
Description
Tyrosol, or 4-(2-hydroxyethyl)phenol, is an antioxidant found in olive oil and other foods. It inhibits the effects of compounds such as oxidized LDL cholesterol. Furthermore, researchers have found that in some microbes, tyrosol acts as a quorum-sensing molecule. A quorum-sensing molecule coordinates activity among groups of many single-celled organisms, such as those that cause yeast infections.
Chemical properties
off-white to light beige crystals or crystalline
The Uses of 4-Hydroxyphenethyl alcohol
Tyrosol (Metoprolol EP Impurity G) is a phenolic antioxidant.
Definition
ChEBI: A phenol substituted at position 4 by a 2-hydroxyethyl group.
Biochem/physiol Actions
Antioxidant found in olive oil.
Properties of 4-Hydroxyphenethyl alcohol
Melting point: | 89-92 °C(lit.) |
Boiling point: | 195°C (18 mmHg) |
Density | 1.0742 (rough estimate) |
refractive index | 1.5590 (estimate) |
Flash point: | 139°C/1mm |
storage temp. | Store below +30°C. |
solubility | 124g/l |
pka | 10.17±0.13(Predicted) |
form | Crystals or Crystalline Powder |
color | Off-white to light beige |
Odor | at 100.00 %. mild sweet floral fruity |
Water Solubility | slightly soluble |
BRN | 1859884 |
CAS DataBase Reference | 501-94-0(CAS DataBase Reference) |
NIST Chemistry Reference | Benzeneethanol, 4-hydroxy-(501-94-0) |
EPA Substance Registry System | 4-Hydroxybenzeneethanol (501-94-0) |
Safety information for 4-Hydroxyphenethyl alcohol
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Hydroxyphenethyl alcohol
InChIKey | YCCILVSKPBXVIP-UHFFFAOYSA-N |
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