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HomeProduct name list4-(Dimethylamino)cinnamaldehyde

4-(Dimethylamino)cinnamaldehyde

Synonym(s):4-(Dimethylamino)-cinnamaldehyde;4-(Dimethylamino)-cinnamaldehyde solution;DMAC;DMACA

  • CAS NO.:6203-18-5
  • Empirical Formula: C11H13NO
  • Molecular Weight: 175.23
  • MDL number: MFCD00007002
  • EINECS: 228-267-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-06 16:20:44
4-(Dimethylamino)cinnamaldehyde Structural

What is 4-(Dimethylamino)cinnamaldehyde?

Chemical properties

white to light yellow crystal powde

The Uses of 4-(Dimethylamino)cinnamaldehyde

4-(Dimethylamino)cinnamaldehyde is a reagent for assay of indole product of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.

The Uses of 4-(Dimethylamino)cinnamaldehyde

4-(Dimethylamino)cinnamaldehyde is a reagent used in the assay of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.

The Uses of 4-(Dimethylamino)cinnamaldehyde

Used to determine the ability of an organism to split indole from the tryptophan molecule.

What are the applications of Application

4-(Dimethylamino)cinnamaldehyde is a reagent used in the assay of apotryptophanase & tryptophanase

Definition

ChEBI: 4-dimethylaminocinnamaldehyde is a member of cinnamaldehydes.

General Description

DMACA is basically a selective staining reagent. It helps identify the flavanols by staining them blue in color.

Biochem/physiol Actions

Reagent for assay of indole product of apotryptophanase and tryptophanase. DMAC produces colored adducts with flavanols for subsequent HPLC. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.

Purification Methods

The aldehyde crystallises from EtOH or ligroin and is dried in vacuo. The oxime has m 157o (from ligroin). The phenylhydrazone has m 169o (form MeOH). It is used as a reagent for amines (with NH3, UV has max at 630nm). [K.nig et al. Chem Ber 61 2075 2075, Quareshi & Kahn Anal Chim Acta 86 309 1976, Beilstein 14 III 184, 14 IV 197.]

Properties of 4-(Dimethylamino)cinnamaldehyde

Melting point: 138-140 °C(lit.)
Boiling point: 306.53°C (rough estimate)
Density  1.0582 (rough estimate)
refractive index  1.5260 (estimate)
storage temp.  -20°C
solubility  dioxane: 50 mg/mL, clear
form  Powder
pka 4.59±0.24(Predicted)
color  Yellow to orange
Sensitive  Air & Light Sensitive
BRN  972369
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference 6203-18-5(CAS DataBase Reference)
NIST Chemistry Reference 2-Propenal, 3-[4-(dimethylamino)phenyl]-(6203-18-5)
EPA Substance Registry System 2-Propenal, 3-[4-(dimethylamino)phenyl]- (6203-18-5)

Safety information for 4-(Dimethylamino)cinnamaldehyde

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P273:Avoid release to the environment.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-(Dimethylamino)cinnamaldehyde

InChIKey RUKJCCIJLIMGEP-ONEGZZNKSA-N

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