4-(Dimethylamino)cinnamaldehyde
Synonym(s):4-(Dimethylamino)-cinnamaldehyde;4-(Dimethylamino)-cinnamaldehyde solution;DMAC;DMACA
- CAS NO.:6203-18-5
- Empirical Formula: C11H13NO
- Molecular Weight: 175.23
- MDL number: MFCD00007002
- EINECS: 228-267-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-06 16:20:44
What is 4-(Dimethylamino)cinnamaldehyde?
Chemical properties
white to light yellow crystal powde
The Uses of 4-(Dimethylamino)cinnamaldehyde
4-(Dimethylamino)cinnamaldehyde is a reagent for assay of indole product of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
The Uses of 4-(Dimethylamino)cinnamaldehyde
4-(Dimethylamino)cinnamaldehyde is a reagent used in the assay of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
The Uses of 4-(Dimethylamino)cinnamaldehyde
Used to determine the ability of an organism to split indole from the tryptophan molecule.
What are the applications of Application
4-(Dimethylamino)cinnamaldehyde is a reagent used in the assay of apotryptophanase & tryptophanase
Definition
ChEBI: 4-dimethylaminocinnamaldehyde is a member of cinnamaldehydes.
General Description
DMACA is basically a selective staining reagent. It helps identify the flavanols by staining them blue in color.
Biochem/physiol Actions
Reagent for assay of indole product of apotryptophanase and tryptophanase. DMAC produces colored adducts with flavanols for subsequent HPLC. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
Purification Methods
The aldehyde crystallises from EtOH or ligroin and is dried in vacuo. The oxime has m 157o (from ligroin). The phenylhydrazone has m 169o (form MeOH). It is used as a reagent for amines (with NH3, UV has max at 630nm). [K.nig et al. Chem Ber 61 2075 2075, Quareshi & Kahn Anal Chim Acta 86 309 1976, Beilstein 14 III 184, 14 IV 197.]
Properties of 4-(Dimethylamino)cinnamaldehyde
Melting point: | 138-140 °C(lit.) |
Boiling point: | 306.53°C (rough estimate) |
Density | 1.0582 (rough estimate) |
refractive index | 1.5260 (estimate) |
storage temp. | -20°C |
solubility | dioxane: 50 mg/mL, clear |
form | Powder |
pka | 4.59±0.24(Predicted) |
color | Yellow to orange |
Sensitive | Air & Light Sensitive |
BRN | 972369 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
CAS DataBase Reference | 6203-18-5(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Propenal, 3-[4-(dimethylamino)phenyl]-(6203-18-5) |
EPA Substance Registry System | 2-Propenal, 3-[4-(dimethylamino)phenyl]- (6203-18-5) |
Safety information for 4-(Dimethylamino)cinnamaldehyde
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(Dimethylamino)cinnamaldehyde
InChIKey | RUKJCCIJLIMGEP-ONEGZZNKSA-N |
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